Results 251 to 260 of about 2,866,239 (361)

Molecular Creep Induced Fatigue Rupture of Fibrin Clots

Advanced Science, EarlyView.
Fibrin networks in thrombi paradoxically exhibit low fatigue resistance despite high fracture energy, as cyclic loading triggers irreversible α‐to‐β transitions in fibrin molecules, causing molecular creep, crack propagation. Multiscale experiments, modeling reveal how nanoscale conformational damage accumulates, linking molecular disorder to ...
Dani Liu, Zichang Jia, Binchao Liu, Jizhe Hou, Rui Bao, Mingkun Wang   +5 more
wiley   +1 more source

Pregnancy and Lactation Associated Bone Fragility. [PDF]

J Endocr Soc
Kovacs CS.
europepmc   +1 more source

Tead1a Initiates Transcriptional Priming Through the TEAD1a/YAP‐Notch1‐Spi1/Cebpα Axis to Promote Neutrophil Fate

Advanced Science, EarlyView.
This study discovered that the protein TEAD1a is crucial for neutrophil development. In zebrafish models, disrupting TEAD1a or its interaction with partner protein YAP1 caused severe neutrophil deficiency. TEAD1a functions during the early HSC stage, activates Notch1 signaling in the GMP stage, and triggers Spi1 and Cebpα to drive neutrophil terminal ...
Wang Yiqin, Yang Ruimeng, Wang Peihong, Liu Xiaohui, Yuan Hao, Huang Hongli, Zhou Yongjian, Xie Baoshu   +7 more
wiley   +1 more source

Lifetime follow-up of an adult patient with pediatric-onset hypophosphatasia complicated with advanced chronic kidney disease. [PDF]

Bone Rep
Sääf M, Björnsdottir S, Haarhaus M, Hauge EM, Atanasova D, Magnusson P.   +5 more
europepmc   +1 more source

Stretchable and Biodegradable Thermally Expandable Composites with Microfluidics for On‐Demand and Programmable Destruction of Electronics

Advanced Science, EarlyView.
Soft, stretchable, thermally expandable composites that enable tunable, mechanically driven, on‐demand destruction of transient electronics are developed. Integrated with microfluidics and wireless circuits, the composites facilitate precise, selective device collapse and frequency‐controlled drug release, highlighting the broad potential in ...
Chan‐Hwi Eom, Won Bae Han, Sungkeun Han, So Jeong Choi, Ikkyo Choi, Jeonguk Kim, Hyewon Cho, Li‐Hyun Kim, Venkata Ramesh Naganaboina, Gwan‐Jin Ko, Tae‐Min Jang, Suk‐Won Hwang   +11 more
wiley   +1 more source

Sono‐Controllable Janus Hydrogel Platform for Sequential Tumor Eradication and Bone Regeneration in Metastatic Breast Cancer

Advanced Science, EarlyView.
Sequential tumor eradication and bone regeneration remain a significant challenge for patients with breast cancer bone metastases. This study develops a novel Janus hydrogel platform, which can achieve tumor elimination and bone repair under the action of different ultrasound frequencies.
Yitong Li, Yunyun Liu, Chuyun Lou, Xuejun Chen, Ying Zhang, Hui Shi, Jiayi Qiu, Shen Zhang, Taixia Wang, Xiaowei Wang, Haohao Yin, Huixiong Xu, Yifeng Zhang   +12 more
wiley   +1 more source

Salvage of a Distal Ulnar Nonunion with Teriparatide Therapy. [PDF]

J Hand Surg Glob Online
Unadkat K, Payne C, Thompson BM, Hassebrock JD, Noland SS, Kruger EA.   +5 more
europepmc   +1 more source

CGRP‐Loaded ROS‐Responsive Hydrogel Restores Neuro‐Angiogenic Signaling to Promote Bone Regeneration in Diabetes‐Associated Periodontitis

Advanced Science, EarlyView.
This study shows that diabetes damages sensory nerve fibers, especially CGRP‐positive ones, in the periodontium and disrupts autophagy in trigeminal ganglion neurons, affecting bone homeostasis by inhibiting type H vessel formation. To address this, CGRP@PVA/tsPBA hydrogels are developed to release CGRP in response to ROS, which binds to endothelial ...
Chaoning Zhan, Qingyi Dai, Jianhan Ren, Lijian Jin, Weiping Wang, Zhou Ye, James Kit Hon Tsoi, Yifan Lin   +7 more
wiley   +1 more source

Apical Fracture of One-Piece Titanium-Zirconium Mini-Implant for Mandibular Overdenture: A Prospective 3-Year Follow-Up. [PDF]

Clin Implant Dent Relat Res
Leles CR, Curado TFF, Leles JLR, Costa NL, Fonseca M, Schimmel M, McKenna G.   +6 more
europepmc   +1 more source

Low‐Temperature Annealing Triggered Abnormal Strengthening in a Complex Concentration Alloy via Evolutive Short‐Range Ordering

Advanced Science, EarlyView.
Low‐temperature annealing enhances strength, ductility, and work hardening in CoNiV MEA. This originates from multi‐scale chemical short‐range orderings (SROs) formed during annealing, which promote dislocation slip planarity and reduce entanglement, enabling balanced mechanical properties through ordering strengthening.
Yihan Wang, Yuan Wu, Yong Yu, Yang He, Xinyang Yu, Xiongjun Liu, Hui Wang, Suihe Jiang, Xiaobin Zhang, Zhaoping Lu   +9 more
wiley   +1 more source