Results 51 to 60 of about 2,866,239 (361)

Bone Health, Fragility Fractures, and the Hand Surgeon

Journal of Hand Surgery Global Online
Fragility fractures, which are often linked to osteoporosis, are fractures resulting from minimal trauma or low-impact falls. Although osteoporosis treatment can reduce risk of fragility fractures, many patients do not meet diagnostic criteria for ...
Jessica Ong, MD, PhD, Isabel Snee, BS, Isabel Marcano, MD, Scott Tintle, MD, Malek Cheikh, MD, Aviram M. Giladi, MD, MS   +5 more
doaj   +1 more source

Alzheimer’s disease and its associated risk of bone fractures: a narrative review

Frontiers in Endocrinology, 2023
BackgroundAlzheimer’s disease (AD) is a neurodegenerative disorder that is the major cause of dementia in the aged population. Recent researches indicate that patients with AD have a significantly increased fracture risk, but the pathological mechanisms ...
Bing-Na Zhou, Qian Zhang, Mei Li
doaj   +1 more source

High serum osteopontin levels are associated with prevalent fractures and worse lipid profile in post-menopausal women with type 2 diabetes [PDF]

, 2018
Purpose: Patients with type 2 diabetes (T2DM) have increased fracture risk. Osteopontin (OPN) is a protein involved in bone remodeling and inflammation.
Carnevale, V., Filardi, Tiziana, Lenzi, A., Massoud, R., Morano, S., Nieddu, L., Romagnoli, E., Russo, C., Tavaglione, F., Turinese, Irene   +9 more
core   +1 more source

Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk

Nature Communications, 2020
Wolff’s law and the Utah Paradigm of skeletal physiology state that bone architecture adapts to mechanical loads. These models predict the existence of a mechanostat that links strain induced by mechanical forces to skeletal remodeling.
Lijun Wang, Xiuling You, S. Lotinun, Lingli Zhang, Nan Wu, Weiguo Zou   +5 more
semanticscholar   +1 more source

Design and motion control of a 6-UPS fully parallel robot for long bone fracture reduction : a thesis presented in partial fulfillment of the requirements for the degree of Master of Engineering in Mechatronics at Massey University [PDF]

, 2007
The incidences of long bone fractures in New Zealand are approximately 1 in 10,000. Long bones such as tibia and femur have complicated anatomic structures, making the realignment of these long bone fractures reliant on the skill of the surgeon.
Wu, Yimin
core  

EXOGEN ultrasound bone healing system for long bone fractures with non-union or delayed healing: a NICE medical technology guidance [PDF]

, 2014
Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are ...
Ailish Higgins, B Campbell, B Livani, C Rubin, Catherine Meads, D Gebauer, E Mayr, I Willits, J White, Joanne Lord, K Withers, LJ Donaldson, M Schofer, M Taylor, Matthew Glover, PA Nolte, S Jingushi, S Rutten, Susan Bayliss, Yaling Yang   +19 more
core   +1 more source

Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos, Maja Mustapic, Carlos Nogueras‐Ortiz, Francheska Delgado‐Peraza, Krishna A. Pucha, Pamela J. Yao, Joseph Blommer, Michael P. Vreones, William York, De' Larrian Knight, Stephen R. Rapp, Aladdin H. Shadyab, JoAnn E. Manson, Ramon Casanova, Robert B. Wallace, Luigi Ferrucci, Susan M. Resnick, Dimitrios Kapogiannis   +17 more
wiley   +1 more source

Modulation of the Inflammatory Response and Bone Healing

Frontiers in Endocrinology, 2020
The optimal treatment for complex fractures and large bone defects is an important unsolved issue in orthopedics and related specialties. Approximately 5–10% of fractures fail to heal and develop non-unions.
Masahiro Maruyama, C. Rhee, T. Utsunomiya, Ning Zhang, Masaya Ueno, Z. Yao, S. Goodman   +6 more
semanticscholar   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

Fracture Nasal Bones [PDF]

, 2013
Nose is the most prominent part of the face, hence it is likely to be the most common structure to be injured in the face.  Although fractures involving the nasal bones are very common, it is often ignored by the patient.
Thiagarajan, Balasubramanian, Ulaganathan, Venkatesan   +1 more
core   +1 more source