Results 41 to 50 of about 57,900 (317)

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan   +5 more
wiley   +1 more source

Marching Fractures [PDF]

open access: yesScientific American, 1917
n ...
openaire   +3 more sources

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

Introduction (Policy Debates on Hydraulic Fracturing)

open access: yes, 2016
Hydraulic fracturing is one of the most contentious issues in environmental and energy politics today. This chapter offers an introduction to the nature of this debate, the rationale for studying the coalitions and public policies surrounding hydraulic ...
Weible, Christopher M.   +7 more
core   +1 more source

Modeling for Volume-Fracturing Vertical Wells in Tight Oil Reservoir considering NMR-Based Research on Imbibition

open access: yes, 2022
The lateral broadband fracturing (LBF) technique for vertical well in tight oil reservoir has been proven to provide much larger stimulated reservoir volume (SRV) by widening its width. Although this new fracturing technique has been successfully applied
Zhiyuan Wang   +4 more
core   +1 more source

Associations of Sleep and Shift Work With Osteoarthritis Risk

open access: yesArthritis Care &Research, EarlyView.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik   +5 more
wiley   +1 more source

Seismo-hydromechanical interaction during in-situ hydraulic fracturing experiments

open access: yes, 2020
PhD, Université de Neichâtel, Centre d'hydrogéologie et de géothermieHydraulic fracturing is a common technique used in a variety of fields like civil and mining engineering, oil & gas and geothermal industry.
Dutler, Nathan
core   +2 more sources

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

open access: yesArthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie   +3 more
wiley   +1 more source

Failure Mechanism of Rock Specimens with a Notched Hole under Compression—A Numerical Study

open access: yesApplied Sciences, 2021
Discontinuities are natural structures that exist in rocks and can affect the stability of rock structures. In this article, the influence of notch presence on the strength and failure evolution around a hole in compressed rock specimens is investigated ...
Amin Manouchehrian   +2 more
doaj   +1 more source

Evaluating a Pragmatic Strength Alternative for Frailty Measurement and Assessing Its Predictive Capacity Against Established Frailty Instruments in Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Frailty occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health outcomes. We compared the performance of four frailty instruments, including a pragmatic alternative measure using chair sit‐to‐stand (STS), and evaluated their abilities to predict poor health outcomes.
Kylie E. Riggles   +14 more
wiley   +1 more source

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