Results 41 to 50 of about 57,900 (317)
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
Introduction (Policy Debates on Hydraulic Fracturing)
Hydraulic fracturing is one of the most contentious issues in environmental and energy politics today. This chapter offers an introduction to the nature of this debate, the rationale for studying the coalitions and public policies surrounding hydraulic ...
Weible, Christopher M. +7 more
core +1 more source
The lateral broadband fracturing (LBF) technique for vertical well in tight oil reservoir has been proven to provide much larger stimulated reservoir volume (SRV) by widening its width. Although this new fracturing technique has been successfully applied
Zhiyuan Wang +4 more
core +1 more source
Associations of Sleep and Shift Work With Osteoarthritis Risk
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik +5 more
wiley +1 more source
Seismo-hydromechanical interaction during in-situ hydraulic fracturing experiments
PhD, Université de Neichâtel, Centre d'hydrogéologie et de géothermieHydraulic fracturing is a common technique used in a variety of fields like civil and mining engineering, oil & gas and geothermal industry.
Dutler, Nathan
core +2 more sources
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie +3 more
wiley +1 more source
Failure Mechanism of Rock Specimens with a Notched Hole under Compression—A Numerical Study
Discontinuities are natural structures that exist in rocks and can affect the stability of rock structures. In this article, the influence of notch presence on the strength and failure evolution around a hole in compressed rock specimens is investigated ...
Amin Manouchehrian +2 more
doaj +1 more source
Objective Frailty occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health outcomes. We compared the performance of four frailty instruments, including a pragmatic alternative measure using chair sit‐to‐stand (STS), and evaluated their abilities to predict poor health outcomes.
Kylie E. Riggles +14 more
wiley +1 more source

