Results 231 to 240 of about 28,649 (270)

Fragile X Mental Retardation Protein Restricts Small Dye Iontophoresis Entry into Central Neurons. [PDF]

J Neurosci, 2017
Kennedy T, Broadie K.
europepmc   +1 more source

Altered Translational Control of Fragile X Mental Retardation Protein on Myelin Proteins in Neuropsychiatric Disorders. [PDF]

Biomol Ther (Seoul), 2017
Jeon SJ, Ryu JH, Bahn GH.
europepmc   +1 more source

Fragile X Mental Retardation Protein and Dendritic Local Translation of the Alpha Subunit of the Calcium/Calmodulin-Dependent Kinase II Messenger RNA Are Required for the Structural Plasticity Underlying Olfactory Learning

, 2015
Laura Daroles, Simona Gribaudo, Mohamed Doulazmi, Sophie Scotto‐Lomassese, Caroline Dubacq, Nathalie Mandairon, Charles A. Greer, Anne Didier, Alain Trembleau, Isabelle Caillé   +9 more
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Absence of the Fragile X Mental Retardation Protein results in defects of RNA editing of neuronal mRNAs in mouse. [PDF]

RNA Biol, 2017
Filippini A, Bonini D, Lacoux C, Pacini L, Zingariello M, Sancillo L, Bosisio D, Salvi V, Mingardi J, La Via L, Zalfa F, Bagni C, Barbon A.   +12 more
europepmc   +1 more source

Increased Calcium Influx through L-type Calcium Channels in Human and Mouse Neural Progenitors Lacking Fragile X Mental Retardation Protein. [PDF]

Stem Cell Reports, 2018
Danesi C, Achuta VS, Corcoran P, Peteri UK, Turconi G, Matsui N, Albayrak I, Rezov V, Isaksson A, Castrén ML.   +9 more
europepmc   +1 more source

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The Fragile X mental retardation protein

Brain Research Bulletin, 2001
The clinical features of the Fragile X mental retardation syndrome are linked to the absence of the set of protein isoforms, derived from alternative splicing of the Fragile X mental retardation gene 1 (FMR1), and collectively termed FMRP. FMRP is an RNA binding protein that is part of a ribonucleoprotein particle associated to actively translating ...
Bardoni, Barbara, Schenck, Annette, Mandel, Jean-Louis   +2 more
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Fragile X mental retardation protein in plasticity and disease

Journal of Neuroscience Research, 2002
AbstractFragile X syndrome is the most common cause of mental retardation known to be inherited. The syndrome results from the suppressed expression of a single protein, the fragile X mental retardation protein (FMRP). Understanding the function and regulation of FMRP can, therefore, offer insights into both the pathophysiology of fragile X syndrome ...
Peter K. Todd, James S. Malter
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The fragile X mental retardation protein is associated with ribosomes

Nature Genetics, 1996
Fragile X mental retardation syndrome is one of the most common human genetic diseases. Patients carry a methylated expansion of a CGG repeat resulting in the silencing of the FMR1 gene1–5 that codes for a heterogeneous set of proteins (FMRP)6–9. FMRP is abundant in neurons and is also widely expressed, albeit at different levels, in various human and ...
Stephane Woerly, Edouard W. Khandjian, François Rousseau, François Corbin   +3 more
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Manipulating the Fragile X Mental Retardation Proteins in the Frog

2011
The frog is a model of choice to study gene function during early development, since a large number of eggs are easily obtained and rapidly develop external to the mother. This makes it a highly flexible model system in which direct tests of gene function can be investigated by microinjecting RNA antisense reagents. Two members of the Fragile X Related
Marc-Étienne Huot, Tom Moss, Nicolas Bisson, Edouard W. Khandjian   +3 more
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Fragile X Mental Retardation Protein and Stem Cells

2011
Stem cells, which can self-renew and produce different cell types, are regulated by both extrinsic signals and intrinsic factors. Fragile X syndrome, one of the most common forms of inherited mental retardation, is caused by the functional loss of fragile X mental retardation protein (FMRP).
Xuekun Li, Peng Jin, Abrar Qurashi
openaire   +3 more sources