Results 71 to 80 of about 5,403 (160)

The Recruitment and Retention of Individuals With Intellectual Disability in Randomized Controlled Trials: A Scoping Review

British Journal of Learning Disabilities, Volume 54, Issue 2, Page 171-211, June 2026.
ABSTRACT Background People with intellectual disabilities face significant health disparities and often encounter barriers in accessing healthcare services. Although research supports the need for reasonable adjustments to improve healthcare access for this population, implementation in acute healthcare settings remains limited.
Owen Doody, Louise Murphy, Ruth Ryan, Rosemary Lyons, Wenyi Tang, Lorna Bourke   +5 more
wiley   +1 more source

A bio‐ecological model for early screening of developmental coordination disorder

Developmental Medicine &Child Neurology, Volume 68, Issue 6, Page 774-783, June 2026.
This original article is commented by Khan et al. on page 740 of this issue. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.70069 Abstract Aim To develop and externally validate a bio‐ecological model for early screening of developmental coordination disorder (DCD) using maternal and environmental risk factors from electronic ...
Xiaotian Dai, Tai Ren, Gareth Williams, Gary Jones, Fei Li, Wenchong Du, Jing Hua   +6 more
wiley   +1 more source

Mainstream or special secondary school for the health, education, and well‐being of adolescents with Down syndrome: A systematic review

Developmental Medicine &Child Neurology, Volume 68, Issue 6, Page 755-766, June 2026.
This systematic review identified three studies comparing education, health, social, and self‐care outcomes among adolescents with Down syndrome who attended either mainstream or special secondary school. Two studies reported improved education outcomes among adolescents in mainstream secondary school.
Julia Shumway, Jill Ellis, Bianca Lucia De Stavola, Ruth Gilbert, Ania Zylbersztejn   +4 more
wiley   +1 more source

Closing the Gender Gap in Fragile X Syndrome: Review on Females with FXS and Preliminary Research Findings.

Brain sciences, 2019
Fragile X syndrome (FXS) is a genetic condition known to increase the risk of cognitive impairment and socio-emotional challenges in affected males and females. To date, the vast majority of research on FXS has predominantly targeted males, who usually exhibit greater cognitive impairment compared to females.
Kristi L. Bartholomay, Cindy H. Lee, Jennifer L. Bruno, Amy A. Lightbody, Allan L. Reiss   +4 more
openaire   +2 more sources

Participation, environment, and quality of life in children with cerebral palsy and physical disabilities

Developmental Medicine &Child Neurology, Volume 68, Issue 6, Page 800-809, June 2026.
Abstract Aim To compare and examine relationships between participation, environmental factors, and quality of life (QoL) in children with cerebral palsy and physical disability (CP/PD) and typically developing children. Method Participants were 59 children (6–12 years; 31 females): 30 with CP/PD (mean age 8 years 7 months, standard deviation 1 year 6 ...
Nava Gelkop, Batya Engel‐Yeger
wiley   +1 more source

Learning Potential is Useful in Pre-schoolers with Fragile X and Down Syndrome

Psicología Educativa: Revista de los Psicólogos de la Educación, 2018
This paper examines the performance of both Down syndrome (DS) and Fragile X syndrome (FXS) pre-schoolers in cognitive tasks of nonverbal reasoning and short-term memory (visual and auditory) and the ability to stimulate cognitive functions with a ...
Mª Auxiliadora Robles-Bello, Nieves Valencia-Naranjo, David Sánchez-Teruel   +2 more
doaj   +1 more source

Epigenetic insights into Fragile X Syndrome

Frontiers in Cell and Developmental Biology
Fragile X Syndrome (FXS) is a genetic neurodevelopmental disorder closely associated with intellectual disability and autism spectrum disorders. The core of the disease lies in the abnormal expansion of the CGG trinucleotide repeat sequence at the 5′end ...
Liangqun Xie, Liangqun Xie, Huiying Li, MengLiang Xiao, Ningjing Chen, Xiaoxiao Zang, Yingying Liu, Hong Ye, Chaogang Tang   +8 more
doaj   +1 more source

Clinical Development of Targeted Fragile X Syndrome Treatments: An Industry Perspective

Brain Sciences, 2018
Fragile X syndrome (FXS) is the leading known cause of inherited intellectual disability and autism spectrum disorder. It is caused by a mutation of the fragile X mental retardation 1 (FMR1) gene, resulting in a deficit of fragile X mental retardation ...
Anna W. Lee, Pamela Ventola, Dejan Budimirovic, Elizabeth Berry-Kravis, Jeannie Visootsak   +4 more
doaj   +1 more source

Towards Mechanism‐Informed Treatments for Mental Health

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Neuropsychiatric disorders impose a major global health burden, and current treatments, which historically mostly targeted dopamine and serotonin dysfunctions, often provide only partial, symptomatic relief. This review highlights emerging evidence that additional neuromodulator systems, including acetylcholine, norepinephrine, and endocannabinoids ...
Iker Bengoetxea de Tena, Farhanah Nabilah Sallie, Arvie Rodriguez Abiero, Beatrice Rizzi, Leandro Gabriel Champarini, Elisa Corti, Gianluca Masella, Ariel L. Dunn, Luisa Bandeira Binder, Tyler J. Wenzel, Agustin I. Robles, Roberta G. Anversa, Cécilia Tremblay, Aliance Romain Fokoua, Randriely Merscher Sobreira de Lima, Mateus D'Ávila, Trang T. T. Truong, Jessica C. Pierce, Rui S. Rodrigues, Luis Dinamarca‐Villarroel, Felipe Borges Almeida, Aino‐Kaisa Piironen, Andrey F. L. Aguiar, Andrés M. Jaramillo, Lucas Santos, Anja de Lange, David J. Nutt, Andrew J. Lawrence   +27 more
wiley   +1 more source

Impaired GABA Neural Circuits Are Critical for Fragile X Syndrome

Neural Plasticity, 2018
Fragile X syndrome (FXS) is an inheritable neuropsychological disease caused by silence of the fmr1 gene and the deficiency of Fragile X mental retardation protein (FMRP).
Fei Gao, Lijun Qi, Zhongzhen Yang, Tao Yang, Yan Zhang, Hui Xu, Huan Zhao   +6 more
doaj   +1 more source