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Fragility Fractures

The Journal of Bone & Joint Surgery, 2005
“Our hope is that Americans can live long and live well. Unfortunately, fractures—the most common and devastating consequence of bone disease—frequently make it difficult...” “Much of the burden of bone disease can potentially be avoided if at-risk individuals are identified and appropriate interventions... are... timely....
Laura L. Tosi, Richard F. Kyle
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Fragile Bones and Fragile Ears

Clinical Orthopaedics and Related Research, 1981
Conductive, sensorineural and mixed hearing loss occur in osteogenesis imperfecta in autosomal dominant inheritance pattern. Hearing loss is generally due to the middle and inner ear pathology of osteogenesis imperfecta and only occasionally to the coincidental association of otosclerosis and osteogenesis imperfecta.
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Fragile Chromosomes

Pediatrics, 1982
The recent article by Hecht et al1 provided a comprehensive summary of this area of genetics that is of particular importance to pediatricians. I would like to add two recent findings of interest. First, Webb et a12 have reported a family with a male of normal intelligence and the fragile X marker chromosome.
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