Results 151 to 160 of about 165,831 (331)

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

open access: yesAdvanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo   +5 more
wiley   +1 more source

Ubiquitination‐Driven Reprogramming of Proteostasis in Metastasis

open access: yesAdvanced Science, EarlyView.
The DCAF12–TRiC/CCT axis is a key regulator of metastasis in cancer. By reprogramming proteostasis to ensure efficient protein folding, it drives progression through a dual mechanism: enhancing cancer cell motility and invasiveness while concurrently activating pro‐growth and survival pathways.
Dongping Wei, Jiayan Chen, Yaping Xu
wiley   +1 more source

A MODULAR BISIMULATION CHARACTERISATION FOR FRAGMENTS OF HYBRID LOGIC [PDF]

open access: hybrid
Guillermo Badía   +4 more
openalex   +1 more source

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

open access: yesAdvanced Science, EarlyView.
ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin   +9 more
wiley   +1 more source

The interpolation theorem in fragments of logics [PDF]

open access: green, 1981
Gerard R. Renardel de Lavalette
openalex   +1 more source

Tuning Li+ and Na+ Functionality in Renewable Carbon Electroactive Material Through Site‐Specific Nanostructural Disorder

open access: yesAdvanced Science, EarlyView.
This study presents a selective thermal transformation of polycarbonate into hybrid carbon materials. The structured carbon enhances electrochemical performance, particularly in lithium‐ion systems. Investigations reveal improved bimetallic ion diffusivity through the hybrid microstructure, contributing to excellent charge kinetics.
Montajar Sarkar   +7 more
wiley   +1 more source

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