Results 131 to 140 of about 3,071,234 (393)

Dynamics of core-excited ammonia: disentangling fragmentation pathways by complementary spectroscopic methods

, 2022
Oksana Travnikova, Farzad Hosseini, T. Marchenko, R. Guillemin, Iyas Ismail, Roba Moussaoui, L. Journel, Aleksandar R. Milosavljević, John D. Bozek, Edwin Kukk, R. Püttner, M. N. Piancaśtelli, M. Simon   +12 more
openalex   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The origin of the most iron-poor star

, 2014
We investigate the origin of carbon-enhanced metal-poor (CEMP) stars starting from the recently discovered $\rm [Fe/H]
Chiaki, Gen, Chieffi, Alessandro, Limongi, Marco, Marassi, Stefania, Nozawa, Takaya, Omukai, Kazuyuki, Schneider, Raffaella, Yoshida, Naoki   +7 more
core   +1 more source

The selectivity and specificity of autophagy in drosophila [PDF]

, 2012
Autophagy is a process of cellular self-degradation and is a major pathway for elimination of cytoplasmic material by the lysosomes. Autophagy is responsible for the degradation of damaged organelles and protein aggregates and therefore plays a ...
Chou, Clark, Contamine, Deng, Dezelee, Finley, Fouillet, Goto, Kadandale, McPhee, Midorikawa, Nezis, Nisoli, Novak, Orvedahl, Pankiv, Park, Rello-Varona, Schweers, Shoji, Simonsen, Tian, Webb, Wild, Wyers, Yu, Yu, Ziviani   +27 more
core   +2 more sources

A Hidden Pathway for Human Exposure to Micro- and Nanoplastics—The Mechanical Fragmentation of Plastic Products during Daily Use [PDF]

, 2023
Yang Yu, Nicholas J. Craig, Lei Su
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Alkaloid profiling of the traditional Chinese medicine Rhizoma corydalis using high performance liquid chromatography-tandem quadrupole time-of-flight mass spectrometry

Acta Pharmaceutica Sinica B, 2014
Since alkaloids are the major active constituents of Rhizoma corydalis (RC), a convenient and accurate analytical method is needed for their identification and characterization.
Mingqian Sun, Jianxun Liu, Chengren Lin, Lan Miao, Li Lin   +4 more
doaj   +1 more source

Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli [PDF]

, 2018
Priming and activating immune stimuli have profound effects on macrophages, however, studies generally evaluate stimuli in isolation rather than in combination.
Achcar, Fiona, Barrett, Michael P., Goodyear, Carl S., Pountain, Andrew W., Rattigan, Kevin M., Regnault, Clement, Vincent, Isabel M.   +6 more
core   +3 more sources

Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure

EMBO Journal, 2014
Adrenergic stimulation of brown adipocytes (BA) induces mitochondrial uncoupling, thereby increasing energy expenditure by shifting nutrient oxidation towards thermogenesis.
J. Wikstrom, Kiana Mahdaviani, M. Liesa, Samuel B. Sereda, Yaguang Si, G. Las, G. Twig, N. Petrovic, Cristina M. Zingaretti, Adam Graham, S. Cinti, B. Corkey, B. Cannon, J. Nedergaard, O. Shirihai   +14 more
semanticscholar   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source