Results 71 to 80 of about 3,071,234 (393)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

A role for tubular networks and a COP I-independent pathway in the mitotic fragmentation of Golgi stacks in a cell-free system

Journal of Cell Biology, 1995
Golgi stacks were previously shown to be converted into tubular networks when incubated in mitotic cytosol depleted of the coatomer subunit of COP I coats (Misteli and Warren, 1994).
T. Misteli, G. Warren
semanticscholar   +1 more source

The fragmentation pathways of protonated glycine: A computational study

Journal of the American Society for Mass Spectrometry, 2000
Numerous studies have demonstrated that protonated aliphatic amino acids, [H2NCHRCO2H + H]+, fragment in the gas phase to form iminium ions, H2N=CHR+. Unfortunately none of these studies have probed the structure of the neutral(s) lost as well as the mechanism of fragmentation.
O’Hair, Richard A.J., Broughton, Peggy S., Styles, Michelle L., Frink, Brian T., Hadad, Christopher M.   +4 more
openaire   +2 more sources

Fragmentation pathways of tungsten hexacarbonyl clusters upon electron ionization [PDF]

The Journal of Chemical Physics, 2016
Electron ionization of neat tungsten hexacarbonyl (W(CO)6) clusters has been investigated in a crossed electron-molecular beam experiment coupled with a mass spectrometer system. The molecule is used for nanofabrication processes through electron beam induced deposition and ion beam induced deposition techniques.
M. Neustetter, E. Jabbour Al Maalouf, P. Limão-Vieira, S. Denifl   +3 more
openaire   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Rapid deconvolution of low-resolution time-of-flight data using Bayesian inference [PDF]

, 2019
The deconvolution of low-resolution time-of-flight data has numerous advantages, including the ability to extract additional information from the experimental data.
Bernardo J. M., Cornelius L. Pieterse, Hans C. Eggers, Mamyrin B. A., Michiel B. de Kock, Press W. H., R. J. Dwayne Miller, Wesley D. Robertson   +7 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Mass spectrometric analysis of purine de novo biosynthesis intermediates.

PLoS ONE, 2018
Purines are essential molecules for all forms of life. In addition to constituting a backbone of DNA and RNA, purines play roles in many metabolic pathways, such as energy utilization, regulation of enzyme activity, and cell signaling.
Lucie Mádrová, Matyáš Krijt, Veronika Barešová, Jan Václavík, David Friedecký, Dana Dobešová, Olga Součková, Václava Škopová, Tomáš Adam, Marie Zikánová   +9 more
doaj   +1 more source

MCM8 is required for a pathway of meiotic double-strand break repair independent of DMC1 in Arabidopsis thaliana.

PLoS Genetics, 2013
Mini-chromosome maintenance (MCM) 2-9 proteins are related helicases. The first six, MCM2-7, are essential for DNA replication in all eukaryotes. In contrast, MCM8 is not always conserved in eukaryotes but is present in Arabidopsis thaliana.
Wayne Crismani, Virginie Portemer, Nicole Froger, Liudmila Chelysheva, Christine Horlow, Nathalie Vrielynck, Raphaël Mercier   +6 more
doaj   +1 more source

A Novel Factor Essential for Unconventional Secretion of Chitinase Cts1

Frontiers in Microbiology, 2020
Subcellular targeting of proteins is essential to orchestrate cytokinesis in eukaryotic cells. During cell division of Ustilago maydis, for example, chitinases must be specifically targeted to the fragmentation zone at the site of cell division to ...
Michèle Reindl, Michèle Reindl, Janpeter Stock, Janpeter Stock, Kai P. Hussnaetter, Kai P. Hussnaetter, Aycin Genc, Andreas Brachmann, Kerstin Schipper, Kerstin Schipper   +9 more
doaj   +1 more source