Results 111 to 120 of about 611,461 (294)

National Council for the Elderly: proceedings of a Conference: Planning Health and Social Care Services for the Elderly: Implications of the Projected Increase in our Elderly Population (1999-2011): Royal Marine Hotel, Dun Laoghaire, Co. Dublin, 24th November 1995.

, 1995
The National Council for the Elderly was established in January 1990 in succession to the National Council for the Aged which began in June. 1981. The terms of reference of the Council are: To advise the Minister for Health of all aspects of ageing ...
National Council for the Elderly
core  

A Global Methane Observation System to Reduce Uncertainty for Anthropogenic and Natural Sources and Sinks for Detecting and Attributing Climate Feedbacks

Advanced Science, EarlyView.
Conceptual illustration of a Global Ecosystem Methane Observing System (GEM‐OS) integrating satellites, aircraft, atmospheric networks, and ecosystem measurements to quantify methane emissions from anthropogenic and natural sources. The multi‐scale observing framework improves source attribution, reduces uncertainty in regional methane budgets, and ...
P. Ciais, S. Peng, J. Chang, F. Li, Q. Zhu, K. Yuan, G. Hugelius, H. Li, Y. Cai, F. Chevallier, K. Tibrewal, E. A. Kort, K. Arndt, J. Watts, B. Buma, N. Besic, P. I. Palmer, H. Cadillo‐Quiroz, E. Euskirchen, M. J. Gondwe, A. Hoyt, R. Jackson, S. Malone, D. Monteverde, S. Natali, M. Ramonet, C. Rey‐Sanchez, L. B. Sagang, E. A. G. Schuur, R. Vargas, R. Varner, Z. Zhang, B. Poulter   +32 more
wiley   +1 more source

Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants

Advanced Science, EarlyView.
A multi‐agent AI system autonomously executes the complete scientific workflow, from hypothesis to manuscript, across three psychological studies involving 288 participants. The system designs experiments, collects real world data, develops analysis pipelines, and writes manuscripts with theoretical rigor comparable to experienced researchers.
Gabrielle Wehr, Reuben Rideaux, Amaya J. Fox, David R. Lightfoot, Jason Tangen, Jason B. Mattingley, Shane E. Ehrhardt   +6 more
wiley   +1 more source

Factors Associated with Physical Frailty in Elderly Women with Low Socioeconomic Status in Urban Communities: A Cross-Sectional Study

Acta Medica Indonesiana, 2019
Background: there are differences in factors associated with frailty syndrome in elderly population. The aim of this research was to determine frailty status (fit, pre-frail and frail) and to identify factors associated with physical frailty in urban ...
Rensa Rensa, Siti Setiati, Purwita W Laksmi, Ikhwan Rinaldi   +3 more
doaj   +2 more sources

Effects of health care interventions on quality of life among frail elderly: a systematized review

, 2019
Jantine van Rijckevorsel-Scheele,1 Renate CWJ Willems,1 Pepijn DDM Roelofs,1 Elin Koppelaar,1 Robbert JJ Gobbens,2–4 Marleen JBM Goumans1 1Research Centre Innovations in Care, Rotterdam University of Applied Sciences, Rotterdam, the Netherlands ...
Willems RCWJ, Goumans MJBM, van Rijckevorsel-Scheele J, Roelofs PDDM, Koppelaar E, Gobbens RJJ   +5 more
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A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers

Advanced Science, EarlyView.
Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels, Joana Caria, Edward A. Lemke   +2 more
wiley   +1 more source

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

Developing an assessment based on physical fitness age to evaluate motor function in frail and healthy elderly women

Clinical Interventions in Aging, 2018
Masaki Nakagaichi,1 Yuya Anan,2 Yuto Hikiji,3 Sou Uratani4 1Sports and Life Sciences, National Institute of Fitness and Sports in KANOYA, Kanoya, Japan; 2Department of Nutritional Health, Kwassui Women’s University, Nagasaki, Japan; 3Department of
Nakagaichi M, Anan Y, Hikiji Y, Uratani S   +3 more
doaj  

Reducing avoidable hospital admissions of the frail elderly using intelligent referrals

, 2007
]: From around 50 years of age, the utilisation of hospital services begins to spiral upwards. In Australia patients over 65 years account for 46% of acute hospital bed days and 33% of hospital separations, although they represent only 12% of the total ...
Soar, Jeffrey, Yuginovich, Trudy, Whittaker, Frank   +2 more
core   +1 more source

Probing the Energy Landscape of α‐Synuclein Amyloid Fibril Formation by Systematic K‐to‐Q Mutagenesis

Advanced Science, EarlyView.
We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka, Azad Farzadfard, Jacob Aunstrup Larsen, Rasmus Krogh Norrild, Federica Saraceno, Celia Fricke, Hossein Mohammad‐Beigi, Ahmed Sadek, Jonas Folke, Susana Aznar, Alexander K. Buell   +10 more
wiley   +1 more source