Results 221 to 230 of about 28,339 (262)

Unraveling the Heterogeneity of Cargo Distribution in the Exogenous Association of Proteins With Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
We characterized the distribution of cargo proteins associated with extracellular vesicles using various exogenous loading methods. In all cases, single‐particle analysis revealed that the distribution of protein content per EV is heterogeneous, following an exponential decay function.
Karl Normak, Marcell Papp, Carolina Paganini, Andrea Zendrini, Paolo Bergese, Dorothea Pinotsi, Paolo Arosio   +6 more
wiley   +1 more source

Multi-Camera Calibration Using Far-Range Dual-LED Wand and Near-Range Chessboard Fused in Bundle Adjustment. [PDF]

Sensors (Basel)
Jatesiktat P, Lim GM, Ang WT.
europepmc   +1 more source

Novel Bioconjugate Materials: Synthesis, Characterization and Medical Applications

Advanced Healthcare Materials, EarlyView.
This review discusses the bioconjugation of novel materials grouped under “biological”, “hybrid” and “synthetic” categories. Medical applications ranging from cancer therapy and diagnostics to optogenetics and tissue engineering are explored, and conjugation trends are highlighted as a general guide. The review concludes with a comparison of techniques
Ellie Martin, Sean P. Doidge, Eiman Aleem, Suela Kellici, Steven Dunn, Claire Atkinson, Philip D. Howes   +6 more
wiley   +1 more source

Antimicrobial stewardship interventions reduce the time to the first antibiotic administration in septic patients in ICUs: regional multicenter study in 7 Latin American high-complexity hospitals. [PDF]

Antimicrob Agents Chemother
García-Betancur JC, Pallares CJ, Restrepo-Arbeláez N, De La Cadena E, Cornistein W, Byró PS, Boldim-Ferreira D, Ahumada R, Valdebenito N, Chaverri-Murillo J, Castañeda-Méndez P, Toledo I, Vente EY, Hercilla L, Moreno V, Goff DA, Villegas MV.   +16 more
europepmc   +1 more source

Engineering Cortical Networks: An Open Platform for Controlled Human Circuit Formation and Synaptic Analysis In Vitro

Advanced Healthcare Materials, EarlyView.
An advanced on‐chip cortical network platform merges human stem cell‐derived neurons with microfabricated devices, enabling precise large‐format circuit design, optogenetic control, and molecular dissection of synaptic formation. This innovative system offers a powerful new tool to explore and model brain connectivity, disease mechanisms, can serve as ...
Pacharaporn Suklai, Taylor Minckley, Cathleen Hagemann, Karolina Faber, Rosalind Norkett, Ludovica Guetta, Kelly O'Toole, Bethany Geary, Michael J. Devine, Andrea Serio   +9 more
wiley   +1 more source

Assessment of ventricular systolic rotation and deformation in premature ventricular contractions of different origins via three-dimensional speckle tracking imaging. [PDF]

Quant Imaging Med Surg
Zhou L, Yu L, Zhong J, Wu B, Zheng L.
europepmc   +1 more source

Facile Deep Brain Electrode Coating with MXene for Improved Electrode Performance

Advanced Healthcare Materials, EarlyView.
Facile dip‐coating of commercial carbon fiber electrodes with Ti3C2Tx MXene improves electrical conductivity, reduces impedance, and enables single‐neuron recordings in the rat hippocampus over four weeks. The coating maintains biocompatibility, minimizes inflammation, and remains MRI‐compatible.
Laura Kondrataviciute, Taufik A. Valiante, Luka Milosevic, Lorraine V. Kalia, Dong Wook Kim, Suneil K. Kalia   +5 more
wiley   +1 more source

Case Report: Loss-of-function TRPM4 mutation p.L91Δ implicated in progressive cardiac conduction defect. [PDF]

Front Physiol
Hämmerli AF, Ross-Kaschitza D, Arullampalam P, Shestak A, Jyh-Ming Juang J, El Makhzen N, Ricciardi BSS, Bokhobza AFE, Rougier JS, Zaklyazminskaya EV, Gajek J, Hasdemir C, Abriel H.   +12 more
europepmc   +1 more source

Tapered Pillar Design for High‐Precision Force Readout in Miniaturized Engineered Heart Tissues From Human Pluripotent Stem Cells

Advanced Healthcare Materials, EarlyView.
Engineered heart tissues (EHTs) are a valuable approach in capturing human cardiac physiology and drug responses in vitro. Here, a novel tapered pillar design is developed in an EHT platform to confine tissues in a predefined position‐ at the middle of the pillar height.
Milica Dostanić, Maury Wiendels, Laura M. Windt, Mervyn P.H. Mol, Francijna E. van den Hil, Richard P. Davis, Valeria Orlova, Berend J. van Meer, Massimo Mastrangeli, Christine L. Mummery   +9 more
wiley   +1 more source

Managing the water-energy-food nexus in the adige river basin: impacts of climate and land use change on ecosystem services bundles. [PDF]

Clim Change
Sambo B, Sperotto A, Aznarez C, Terzi S, Pittore M, Critto A, Torresan S.   +6 more
europepmc   +1 more source