Results 41 to 50 of about 15,487 (310)

Design and Validation of a Low-Level Controller for Hierarchically Controlled Exoskeletons

Sensors, 2023
In this work, a generalized low-level controller is presented for sensor collection, motor input, and networking with a high-level controller. In hierarchically controlled exoskeletal systems, which utilize series elastic actuators (SEAs), the hardware ...
Connor W. Herron, Zachary J. Fuge, Madeline Kogelis, Nicholas J. Tremaroli, Bhaben Kalita, Alexander Leonessa   +5 more
doaj   +1 more source

Reference frames and reference networks

Geodesy and Cartography, 2015
Abstract The summary of research activities concerning reference frames and reference networks performed in Poland in a period of 2011-2014 is presented. It contains the results of research on implementation of IUGG2011 and IAU2012 resolutions on reference systems, implementation of the ETRS89 in Poland, operational work of permanent IGS/ EUREF ...
Bosy Jaroslaw, Krynski Jan
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Design of Rollable Reciprocal Frame Network

Journal of the International Association for Shell and Spatial Structures
In the literature, reciprocal frames have been studied mostly for static structures. Studies on kinetic reciprocal frames are very limited. This study investigates two degrees-of-freedom reciprocal frame fans, and a novel deployable reciprocal frame network is obtained.
Özen, Gülçin, Korkmaz, Koray, Kiper, Gökhan   +2 more
openaire   +2 more sources

Network multiple frame assignment architectures

, 2001
Multiple target tracking methods divide into two broad classes, namely single frame and multiple frame methods. The most successful of the multiple frame methods are multiple hypothesis tracking (MHT) and multiple frame assignments (MFA). In dense tracking environments the performance improvements of multiple frame methods over single frame methods is ...
Lu, Suihua, author, Poore, Aubrey, advisor, Kirby, Michael J., committee member, Zachmann, David W., committee member, Miranda, Rick, 1953-, committee member   +4 more
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The challenge of social networking in the field of environment and health

Environmental Health, 2012
Background The fields of environment and health are both interdisciplinary and trans-disciplinary, and until recently had little engagement in social networking designed to cross disciplinary boundaries.
van den Hazel Peter, Keune Hans, Randall Scott, Yang Aileen, Ludlow David, Bartonova Alena   +5 more
doaj   +1 more source

Functional contextual implementation of an evolutionary, entropy-based, and embodied free energy framework: Utilizing Lagrangian mechanics and evolutionary game theory’s truth vs. fitness test of the veridicality of phenomenological experience

Frontiers in Psychology, 2023
The Bayesian approach of cognitive science largely takes the position that evolution drives perception to produce precepts that are veridical. However, some efforts utilizing evolutionary game theory simulations have shown that perception is more likely ...
Darren J. Edwards
doaj   +1 more source