Results 71 to 80 of about 296,850 (344)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Effective Caching for the Secure Content Distribution in Information-Centric Networking
, 2018 The secure distribution of protected content requires consumer authentication and involves the conventional method of end-to-end encryption. However, in information-centric networking (ICN) the end-to-end encryption makes the content caching ineffective ...
Bilal, Muhammad +2 more
core +1 more source
The challenge of social networking in the field of environment and health
Environmental Health, 2012 Background The fields of environment and health are both interdisciplinary and trans-disciplinary, and until recently had little engagement in social networking designed to cross disciplinary boundaries.
van den Hazel Peter +5 more
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Education Sciences, 2021 For most professionals to succeed in the current job market, they need some entrepreneurial skills (ES). This study aimed to describe and systematize these skills, considering the current globalization and digital transformation phenomena. The documental
Jacinto Jardim
doaj +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Dianxin kexue, 2022 Atmospheric duct interference is a seriousinternal interference of large-scale TDD wireless communication system according to specific meteorological conditions.The causes and classification of the atmospheric duct interference were analyzed firstly.Then
Xiaoyun WANG +4 more
doaj +2 more sources
FEBS Open Bio, EarlyView.Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
Design of campus comprehensive access management platform
Tongxin xuebao, 2013 Considering access control with more card,scattered access flow data and poor scalabiliby in current unirersity building multi-system,the campus integrated access management platform triple frame design with the core of perception layer,transport layer ...
Cai-e XU +4 more
doaj +2 more sources
Pyramidal Predictive Network: A Model for Visual-frame Prediction Based on Predictive Coding Theory [PDF]
, 2022 Chaofan Ling, Junpei Zhong, Weihua Li
openalex +1 more source