Results 91 to 100 of about 2,374,465 (380)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
The reference frame of visual motion priming depends on underlying motion mechanisms.
Several different types of motion mechanisms function in the human visual system. The purpose of this study was to clarify the type of reference frame, such as retinotopic and spatiotopic frames of reference, at which those different motion mechanisms ...
Sanae Yoshimoto +2 more
semanticscholar +1 more source
Consistency of shared reference frames should be reexamined
In a recent Letter [G. Chiribella et al., Phys. Rev. Lett. 98, 120501 (2007)], four protocols were proposed to secretly transmit a reference frame. Here We point out that in these protocols an eavesdropper can change the transmitted reference frame ...
A. Wójcik +15 more
core +1 more source
Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno +12 more
wiley +1 more source
Assistant without Master? Some Conceptual Implications of Assistive Robotics in Health Care
The subject of “technical assistants” in inpatient care is currently being widely discussed in scientific and public circles. In many cases, though, it has become apparent that the umbrella term “assistive technologies”, also in the context of robotics ...
Bettina-Johanna Krings, Nora Weinberger
doaj +1 more source
The cryptographic power of misaligned reference frames
Suppose that Alice and Bob define their coordinate axes differently, and the change of reference frame between them is given by a probability distribution mu over SO(3).
A. Winter +6 more
core +1 more source
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley +1 more source
Informational Reinterpretation of the Mechanics Notions and Laws
The informational re-interpretation of the basic laws of the mechanics exploiting the Landauer principle is suggested. When a physical body is in rest or it moves rectilinearly with the constant speed, zero information is transferred; thus, the ...
Edward Bormashenko
doaj +1 more source
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu +8 more
wiley +1 more source

