Results 51 to 60 of about 515,298 (308)

Think positive: Proposal of a simple method to create reference materials in the frame of microplastics research

MethodsX, 2023
In the context of the harmonization of methodologies employed to isolate and count microplastics in samples or to organize ring trials tests, the use of reference materials, i.e. samples with controlled amount of particles is required.
Alexandre Dehaut, Charlotte Himber, Mathilde Colin, Guillaume Duflos   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Characterizing the Dynamic Response of a Chassis Frame in a Heavy-Duty Dump Vehicle based on an Improved Stochastic System Identification

, 2015
This paper presents an online method for the assessment of the dynamic performance of the chassis frame in a heavy-duty dump truck based on a novel stochastic subspace identification (SSI) method. It introduces the use of an average correlation signal as
Chen, Zhi, Gu, Fengshou, Zhi Chen, Fengshou Gu, Tie Wang, Zhang, Ruiliang, Ruiliang Zhang, Jing, Peng, Wang, Tie   +8 more
core   +1 more source

The Biopsychosocial Model: Application to Occupational Therapy Practice

Open Journal of Occupational Therapy, 2018
Despite the call for the profession to embrace a more integrated and holistic approach to practice, therapists may be faced with practical challenges, including issues relating to client caseloads, productivity demands, scheduling, entrenched practices ...
Keith Gentry, Karen Snyder, Beth Barstow, Jordan Hamson-Utley   +3 more
doaj   +1 more source

Compared to what? Effects of social and temporal comparison standards of feedback in an e-learning context

International Journal of Educational Technology in Higher Education, 2022
Performance evaluation is based on comparison standards. Results can either be contrasted to former results (temporal comparison) or results of others (social comparison). Existing literature analyzed potential effects of teachers’ stable preferences for
Marc P. Janson, Jan Siebert, Oliver Dickhäuser   +2 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Étude de l’activité évaluative de professeurs stagiaires confrontés à des productions d’élèves en mathématiques : quel référent pour l’évaluateur ?

Mesure et Évaluation en Éducation, 2007
Nous étudions l’activité évaluative de dix-huit professeurs stagiaires – professeurs des écoles (enseignement primaire) et professeurs de mathématiques (enseignement secondaire) – confrontés à des productions d’élèves en mathématiques.
Marc Vantourout
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Why Not Just Features? Reconsidering Infants’ Behavior in Individuation Tasks

Frontiers in Psychology, 2020
It counts as empirically proven that infants can individuate objects. Object individuation is assumed to be fundamental in the development of infants’ ontology within the object-first account.
Frauke Hildebrandt, Jan Lonnemann, Ramiro Glauer   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source