Results 81 to 90 of about 2,447,227 (317)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Why Not Just Features? Reconsidering Infants’ Behavior in Individuation Tasks
Frontiers in Psychology, 2020 It counts as empirically proven that infants can individuate objects. Object individuation is assumed to be fundamental in the development of infants’ ontology within the object-first account.
Frauke Hildebrandt +2 more
doaj +1 more source
Integrating Multiple 3D Views through Frame-of-reference Interaction [PDF]
, 2003 Frame-of-reference interaction consists of a unified set of 3D interaction techniques for exploratory navigation of large virtual spaces in nonimmersive environments.
Plumlee, Matthew D, Ware, Colin
core +1 more source
What is the reference frame of an accelerated observer?
, 1998 The general construction of extended refrence frames for noninertial observers in flat space is studied. It is shown that, if the observer moves inertially before and after an arbitrary acceleration and rotation, the region where reference frames can ...
Karl-Peter Marzlin +7 more
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Sophisticated Thinking: Higher Order Thinking Skills
Journal of Language and Education, 2015 The information-based society determines that the key factor to achieve success is the development of sophisticated thinking. That said, the thinking process cannot be just a mere imitation of cognitive work, since the digital age requires the authentic ...
Elena Tikhonova, Natalia Kudinova
doaj +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Revue Archéologique de l’Est, 2016 The building of a typology of objects found in Merovingian burials in Frankish Burgundian Kingdom requires a preliminary definition of the objects "represented in series" that are part of the funerary assemblage from this cultural domain.
Sophie Gizard, René Legoux
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source