Results 71 to 80 of about 50,797 (262)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Tetris Tight Frames Construction via Hadamard Matrices

open access: yesAbstract and Applied Analysis, 2014
We present a new method to construct unit norm tight frames by applying altered Hadamard matrices. Also we determine an elementary construction which can be used to produce a unit norm frame with prescribed spectrum of frame operator.
A. Abdollahi, M. Monfaredpour
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Probability Modeled Optimal K-Frame for Erasures

open access: yesIEEE Access, 2018
It has been found that the research of a special kind of frames, named K-frames where K is an operator, is significant in theory and application. In this paper, first of all, in theory, we discuss some properties about the existence and structure of the ...
He Miao   +3 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Weaving g-Frames for Operators

open access: yesKragujevac Journal of Mathematics
Bemrose et al. introduced weaving frames and later, Deepshikha et al. generalized them to weaving K-frames. In this note, as a generalization of these notions, we introduce approximate K-duals and investigate the properties of K-g-frames and weaving K-g-frames. We show that woven K-g-frames and weakly woven K-g-frames coincide.
Khosravi, A., Banyarani, J. S.
openaire   +2 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Some Properties of Relay Fusion Frames in Finite Dimensions

open access: yesAxioms
In this paper, we analyze the relationship between relay fusion frames and standard fusion frames in finite-dimensional real Hilbert spaces. We propose an optimal design method for tight relay fusion frames in the setting of orthogonal subspaces ...
Jianxia Zhang   +4 more
doaj   +1 more source

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