Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Correction: Zhang et al. The Stressing State Features of a Bottom Frame Structure Revealed from the Shaking Table Strain Data. Materials 2023, 16, 1809. [PDF]
Materials (Basel), 2023 Zhang L +5 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley +1 more source
Performance analysis of NSA control plane and user plane delay in 5G network
Dianxin kexue, 2020 Different from 2G/3G/4G,the 5G network architecture contains two parts:NSA (non-standalone) and SA (standalone) networking.NSA can help network deploys faster.Low latency is a very important feature of 5G,and its implementation requires a combination of ...
Dan ZHANG +3 more
doaj
Preparation and Photocatalytic Properties of Anatase TiO2 with Hollow Hexagonal Frame Structure. [PDF]
Nanomaterials (Basel), 2022 Teng M, Liu H, Lin B, Zhou X, Zhou W.
europepmc +1 more source
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
MachinesThe profile modular system offers variability, flexibility, ease of assembly, and corrosion resistance as well as non-time-consuming assembly while meeting the required conditions of the customer. It has a broad spectrum of usability.
Lenka Jakubovičová +2 more
doaj +1 more source
Research on collapse ultimate load of fabricated reinforced concrete column and steel beam composite frame structure. [PDF]
Sci Rep, 2022 Liu Y, Xiong J, Wen J, Xiong M.
europepmc +1 more source
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source