Results 21 to 30 of about 6,468 (243)

A Comparative Evaluation of Different Diagnostic Modalities in the Diagnosis of Typhoid Fever Using a Composite Reference Standard: A Tertiary Hospital Based Study in Central India [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: Enteric fever, caused by Salmonella spp. is a major cause of morbidity and mortality worldwide and endemic in many developing countries including India and other South-East Asian countries. Blood culture is regarded as the gold standard
Veena Maheshwari   +3 more
doaj   +1 more source

Shear lag phenomenon in the tubular systems with outriggers and belt trusses

open access: yesИнженерно-строительный журнал, 2019
Development of technology facilitates construction of tall buildings. One of the common kinds of them is Tubular systems, divided into different types: framed tube, tube-in-tube, trussed tube and bundled tube systems.
Hamed Arshadi, Ali Kheyroddin
doaj   +1 more source

Study on the Seismic Response Parameters of Steel Medium-Height Buildings with Framed-Tube Skeleton under Near-Fault Records

open access: yesElectronic Journal of Structural Engineering, 2015
In this research, the performance abilities of tube type lateral load resistant framed systems are studied in order to assess the dynamic response properties of mid-rise steel structures under effects of far and near-field ground motions.
M. Azhdarifar   +2 more
doaj   +1 more source

Craniorachischisis - a case report

open access: yesNational Journal of Clinical Anatomy, 2015
Craniorachischisis is an extreme example of anencephaly and spina bifida. It is an example for defective neural groove closure. A female dead fetus delivered by caesarian section in Malla Reddy Medical College, Hyderabad found to have features of ...
N Ratnakar Rao
doaj   +1 more source

Transport of solid bodies along tubular membrane tethers.

open access: yesPLoS ONE, 2019
We study the crucial role of membrane fluctuations in maintaining a narrow gap between a fluid membrane tube and an enclosed solid particle. Solvent flows can occur in this gap, hence giving rise to a finite particle mobility along the tube.
D R Daniels
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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