Results 61 to 70 of about 1,895,438 (316)

JORGE COLAÇO IDENTITY AND TRANSCULTURALITY IN AZULEJO FRAMINGS

open access: yesArt is on, 2016
The azulejo frames of Jorge Colaço here in study present themselves as an independent area, an available space for technical and artistic experimentation, unifying and revealing multiple influences.
Patrícia Nóbrega
doaj  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Single-Frame, Multiple-Frame and Framing Motifs in Genes [PDF]

open access: yesLife, 2019
We study the distribution of new classes of motifs in genes, a research field that has not been investigated to date. A single-frame motif SF has no trinucleotide in reading frame (frame 0) that occurs in a shifted frame (frame 1 or 2), e.g., the dicodon AAACAA is S F as the trinucleotides AAA and CAA do not occur in a shifted frame.
openaire   +4 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Proportional Nonuniform Multi-Gabor Expansions

open access: yesEURASIP Journal on Advances in Signal Processing, 2004
A nonuniform multi-Gabor expansion (MGE) scheme is studied under proportional time and frequency (TF) shifts among different window indices . In particular, TF parameters for each are different, but proportional and relevant to windows' TF patterns ...
Li Shidong
doaj   +1 more source

Fusion frames and g-frames

open access: yesJournal of Mathematical Analysis and Applications, 2008
The authors study generalized, i.e., \(g\)-frames in a Hilbert space \(U\), that is, sequences \((\Lambda_i)_{i\in I}\) of linear operators \(\Lambda_i:U\to V_i\) such that \[ A\| f\| ^2 \leq \sum_{i\in I} \| \Lambda_i f\| ^2 \leq B \| f\| ^2, \] for some positive constants \(A\) and \(B\).
Khosravi, Amir, Musazadeh, Kamran
openaire   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Discrete dualities for Monteiro's tetravalent modal algebras [PDF]

open access: yesJournal of Mahani Mathematical Research
Discrete duality refers to a form of duality in which a class of abstract relational systems serves as the dual counterpart to a class of algebras. These relational systems are called \textit{frames}, following the terminology of non-classical logics. No
Gustavo Pelaitay
doaj   +1 more source

Home - About - Disclaimer - Privacy