Results 71 to 80 of about 794,432 (370)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

“Girding up the Loins”: A Cognitive Sematic Analysis of Humorous Expressions

open access: yesPółrocznik Językoznawczy Tertium, 2016
A large number of humorous linguistic expressions in English (and also in other languages) are characterized by such cognitive processes as metonymy, metaphor, and conceptual integration, or blending.
Zoltán Kövecses
doaj   +1 more source

Convolutional frames and the frame potential

open access: yesApplied and Computational Harmonic Analysis, 2005
AbstractThe recently introduced notion of frame potential has proven useful for the characterization of finite-dimensional tight frames. The present work represents an effort to similarly characterize finite-dimensional tight frames with additional imposed structure.
Kasso A. Okoudjou   +3 more
openaire   +2 more sources

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Beware the Trolley Zealots

open access: yesSociologica, 2020
This essay draws on Mary Douglas' theory of institutional styles of thinking to analyze the debate about how and when the Coronavirus crisis can be brought to an end. The dominant approach, I show, frames the problem in utilitarian terms, akin to what is
Gil Eyal
doaj   +1 more source

Cognitive Frames in Corporate Sustainability: Managerial Sensemaking with Paradoxical and Business Case Frames

open access: yes, 2014
Corporate sustainability confronts managers with tensions between complex economic, environmental, and social issues. Drawing on the literature on managerial cognition, corporate sustainability, and strategic paradoxes, we develop a cognitive framing ...
Tobias Hahn   +3 more
semanticscholar   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Frame Multipliers for discrete frames on Quaternionic Hilbert Spaces [PDF]

open access: yesarXiv, 2018
In this note, following the complex theory, we examine discrete controlled frames, discrete weighted frames and frame multipliers in a non-commutative setting, namely in a left quaternionic Hilbert space. In particular, we show that the controlled frames are equivalent to usual frames under certain conditions.
arxiv  

On excesses of frames [PDF]

open access: yesGlasnik Matematicki, 2015
We show that any two frames in a separable Hilbert space that are dual to each other have the same excess. Some new relations for the analysis resp. synthesis operators of dual frames are also derived. We then prove that pseudo-dual frames and, in particular, approximately dual frames have the same excess.
Damir Bakić, Tomislav Berić
openaire   +3 more sources

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

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