Results 111 to 120 of about 5,283,663 (317)

Understanding barriers to immunization among women with zero-dose or under-immunized children in an urban area in Cameroon

open access: yesFrontiers in Public Health
BackgroundZero-dose children represent a major public health challenge in low-income countries. In 2024, the Nkolndongo Health District in Yaoundé, Cameroon, recorded the highest number of zero-dose children in the country, according to the District ...
Ehouzou Mandeng   +9 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Uncleserj/panda-options-framework: Panda Options Framework Plugin

open access: yes, 2017
<p>Wordpress Options Framework</p ...
Uncleserj
core   +1 more source

Oxidation of 5-hydroxymethylfurfural into 2,5-furandicarboxylic acid over CuO and NiO modified natural sourced hierarchical ZSM-5

open access: yesSouth African Journal of Chemical Engineering
The platform molecule 2,5-furandicarboxylic acid (FDCA) has potential applications. FDCA can be synthesized through the oxidation of 5-hydroxymethylfurfural (HMF). In this study, HMF oxidation to FDCA was conducted over ZSM-5-based catalysts from natural
Idra Herlina   +2 more
doaj   +1 more source

Crystal structures of 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(3-nitrophenyl)acetamide monohydrate and N-(2-chlorophenyl)-2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]acetamide

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2016
The title compounds, C12H12N6O3S·H2O, (I), and C12H12ClN5OS, (II), are 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]acetamides. Compound (I) crystallized as a monohydrate.
S. Subasri   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

GeoStat-Framework/ogs5py v1.0.0

open access: yes, 2019
<p><strong>Purpose</strong></p> <p>ogs5py is A python-API for the <a href="https://www.opengeosys.org/ogs-5/">OpenGeoSys 5</a> scientific modeling package.</p> <p><strong>Installation< ...
Sebastian Müller (631831)   +3 more
core   +1 more source

An analytical framework

open access: yes
Financial markets play a significant role in channelling funds from surplus spending units (fund givers) to deficit spending units (fund takers). Whether financial intermediation is carried out by banks or capital markets, market failures are ubiquitous and call for financial regulation. This chapter studies how different jurisdictions cope with market
Edoardo D. Martino   +2 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy