Results 111 to 120 of about 5,283,663 (317)
It is time to become serious about closing the global resource gap for FCTC implementation
Ryan Forrest, Sara Rose Taylor
doaj +1 more source
BackgroundZero-dose children represent a major public health challenge in low-income countries. In 2024, the Nkolndongo Health District in Yaoundé, Cameroon, recorded the highest number of zero-dose children in the country, according to the District ...
Ehouzou Mandeng +9 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Uncleserj/panda-options-framework: Panda Options Framework Plugin
<p>Wordpress Options Framework</p ...
Uncleserj
core +1 more source
The platform molecule 2,5-furandicarboxylic acid (FDCA) has potential applications. FDCA can be synthesized through the oxidation of 5-hydroxymethylfurfural (HMF). In this study, HMF oxidation to FDCA was conducted over ZSM-5-based catalysts from natural
Idra Herlina +2 more
doaj +1 more source
The title compounds, C12H12N6O3S·H2O, (I), and C12H12ClN5OS, (II), are 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]acetamides. Compound (I) crystallized as a monohydrate.
S. Subasri +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
GeoStat-Framework/ogs5py v1.0.0
<p><strong>Purpose</strong></p> <p>ogs5py is A python-API for the <a href="https://www.opengeosys.org/ogs-5/">OpenGeoSys 5</a> scientific modeling package.</p> <p><strong>Installation< ...
Sebastian Müller (631831) +3 more
core +1 more source
Financial markets play a significant role in channelling funds from surplus spending units (fund givers) to deficit spending units (fund takers). Whether financial intermediation is carried out by banks or capital markets, market failures are ubiquitous and call for financial regulation. This chapter studies how different jurisdictions cope with market
Edoardo D. Martino +2 more
openaire +2 more sources

