A Delphi Study to Identify Priority Indicators for Formulary Selection of Innovative Anticancer Drugs in China. [PDF]
Zhao J +16 more
europepmc +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Correction: A sustainability framework based on threats, consequences, and solutions (TCS) for managing watershed commons. [PDF]
Camarillo ALQ, Randhir TO.
europepmc +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Physician's role(s): Conceptual redesign and implementation of the lecture series "Introduction to clinical medicine" for the promotion of professional identity formation based on the physician's roles of the CanMEDS framework. [PDF]
Schumm M +3 more
europepmc +1 more source
Framework for excellence : a comprehensive performance assessment framework for the further education system [PDF]
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Edge based distributed framework for real time hazard detection and road safety in smart transportation. [PDF]
Sahu D +8 more
europepmc +1 more source

