Results 61 to 70 of about 15,676,085 (372)

Chain of Custody Implementation on Public Service Administration in Indonesia: A Framework

Sorot, 2021
Proses administrasi dapat dilihat melalui proses umum, sedangkan tindakan administratif dapat dilihat pada tingkat program tertentu. Chain of custody (CoC), dalam konteks hukum, mengacu pada dokumentasi kronologis atau jejak kertas yang mencatat urutan ...
Resista Vikaliana, Maya Puspita Dewi, Munir Saputra, Tulus Santoso, Sukarni Novitasari   +4 more
doaj   +1 more source

HEALPix: A Framework for High-Resolution Discretization and Fast Analysis of Data Distributed on the Sphere [PDF]

, 2004
HEALPix—the Hierarchical Equal Area isoLatitude Pixelization—is a versatile structure for the pixelization of data on the sphere. An associated library of computational algorithms and visualization software supports fast scientific applications ...
K. Gorski, E. Hivon, A. Banday, Benjamin Dan Wandelt, F. Hansen, M. Reinecke, M. Bartelman   +6 more
semanticscholar   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Legal Framework of Land Engineering: Compliance with Environmental Regulations to Reduce Pollution

EAI Endorsed Transactions on Energy Web
  Research in relation to land technology should be conducted guided by concerns for environmental sustainability. There must be a robust framework that regulates land use and development, taking into account changes in the environment due to biological,
Xuewen Du
doaj   +1 more source

A framework for consciousness [PDF]

Nature Neuroscience, 2003
Here we summarize our present approach to the problem of consciousness. After an introduction outlining our general strategy, we describe what is meant by the term 'framework' and set it out under ten headings. This framework offers a coherent scheme for explaining the neural correlates of (visual) consciousness in terms of competing cellular ...
Crick, Francis, Koch, Christof
openaire   +3 more sources

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Acceptability of healthcare interventions: an overview of reviews and development of a theoretical framework

BMC Health Services Research, 2017
BackgroundIt is increasingly acknowledged that ‘acceptability’ should be considered when designing, evaluating and implementing healthcare interventions.
Mandeep Sekhon, M. Cartwright, J. Francis   +2 more
semanticscholar   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Who Will Tame the Giants?

Scandinavian Journal for Leadership & Theology, 2023
This article investigates tech giants such as Google, Facebook, and Twitter in the light of the Pauline concepts of principalities and powers. It is argued that as people subjugate themselves to the digital frameworks of these modern giants, the way ...
Lars Öberg
doaj   +1 more source