Results 81 to 90 of about 7,066,530 (335)

Scientific Data Management in the Age of Big Data: An Approach Supporting a Resilience Index Development Effort

Frontiers in Environmental Science, 2019
The increased availability of publicly available data is, in many ways, changing our approach to conducting research. Not only are cloud-based information resources providing supplementary data to bolster traditional scientific activities (e.g., field ...
Linda C. Harwell, Deborah N. Vivian, Michelle D. McLaughlin, Stephen F. Hafner   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Bimetallic NiAg supported on aminopropyl-functionalized periodic mesoporous organosilica as a reusable catalyst for CO2 conversion to value-added chemicals

Journal of Saudi Chemical Society
Transforming CO2 into more valuable chemicals has gained great interest due to greenhouse gas and climate change related issues. In this study, we performed CO2 hydrogenation using a bimetallic nickel-silver catalyst supported on periodic mesoporous ...
Iman Abdullah, Patrik Chandra, Yuni Krisyuningsih Krisnandi   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Embodied Engagement with Narrative: A Design Framework for Presenting Cultural Heritage Artifacts

Multimodal Technologies and Interaction, 2019
An increasing number of museum exhibits incorporate multi-modal technologies and interactions; yet these media divert visitors’ attention away from the cultural heritage artifacts on display.
Jean Ho Chu, Ali Mazalek
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Oxidation of 5-hydroxymethylfurfural into 2,5-furandicarboxylic acid over CuO and NiO modified natural sourced hierarchical ZSM-5

South African Journal of Chemical Engineering
The platform molecule 2,5-furandicarboxylic acid (FDCA) has potential applications. FDCA can be synthesized through the oxidation of 5-hydroxymethylfurfural (HMF). In this study, HMF oxidation to FDCA was conducted over ZSM-5-based catalysts from natural
Idra Herlina, Yuni Krisyuningsih Krisnandi, Muhammad Ridwan   +2 more
doaj   +1 more source

MetaGPT: Meta Programming for Multi-Agent Collaborative Framework

arXiv.org, 2023
Sirui Hong, Xiawu Zheng, Jonathan P. Chen, Yuheng Cheng, Ceyao Zhang, Zili Wang, Steven Ka Shing Yau, Z. Lin, Liyang Zhou, Chenyu Ran, Lingfeng Xiao, Chenglin Wu   +11 more
semanticscholar   +1 more source