Results 141 to 150 of about 972,269 (340)

Fetal glucose availability: a key regulator of the metabolic, hormonal and contractility profiles of the fetal sheep heart

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend To investigate the role of glucose availability in fetal left ventricle (LV) development, this study assessed whether maternal late gestation undernutrition (LGUN; 50% of Control diet) induced alterations in the contractility, metabolic, and hormonal profile can be ameliorated in LGUN fetuses receiving glucose infusion (LGUN+G ...
Melanie R. Bertossa   +10 more
wiley   +1 more source

Gene-environment interactions due to quantile-specific heritability of triglyceride and VLDL concentrations. [PDF]

open access: yes, 2020
"Quantile-dependent expressivity" is a dependence of genetic effects on whether the phenotype (e.g., triglycerides) is high or low relative to its distribution in the population.
Williams, Paul T
core   +1 more source

Epidemiology of Stroke: Legacy of the Framingham Heart Study

open access: yesGlobal Heart, 2013
In the present historical review, we highlight several articles outlining contributions of the Framingham Heart Study over the span of nearly seven decades to our understanding of the epidemiology of blood pressure (BP), atrial fibrillation and genetic factors as they relate to cerebrovascular disease.
Romero, Jose R., Wolf, Philip A.
openaire   +3 more sources

Metastatic Spine Disease Alters Vertebral Load‐To‐Strength Ratios in Cancer Patients Compared to Healthy Individuals

open access: yesJOR SPINE, Volume 9, Issue 1, March 2026.
This study investigated the effect of spinal bone metastasis (BM) on the biomechanical environment of the spine through estimates of load, strength, and the load‐to‐strength ratio (LSR). Our study suggests that task‐specific differences related to cancer, lesion type, and vertebral location differentially affect the biomechanical environment of the ...
Dennis E. Anderson   +13 more
wiley   +1 more source

A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population [PDF]

open access: diamond, 2003
Ming D. Li   +7 more
openalex   +1 more source

Targeting Delivery of Cyanidin‐Loaded With Ti3C2 Nanosheets for Alleviating Vascular Calcification in Chronic Kidney Disease

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.
Vascular calcification significantly elevates cardiovascular risk in CKD patients, yet no effective therapies exist to halt its progression. We developed a dual targeting nanoplatform Ti3C2/RANKL/OCN/Cyanidin (TROC) for the targeted delivery of cyanidin against vascular calcification.
Li Yin   +10 more
wiley   +1 more source

Detection of Dementia on Raw Voice Recordings Using Deep Learning: A Framingham Heart Study

open access: green, 2021
Chonghua Xue   +4 more
openalex   +1 more source

An LC–MS/MS Method for the Quantitation of Metabolites M9, M12, and M20 of Bexicaserin in Human Cerebrospinal Fluid

open access: yesBiomedical Chromatography, Volume 40, Issue 2, February 2026.
ABSTRACT The investigational molecule bexicaserin is a highly selective 5‐HT2C superagonist currently in Phase 3 clinical studies for the treatment of seizures associated with developmental and epileptic encephalopathies (DEEs). To facilitate its clinical development, a simple LC–MS/MS method was developed and validated for the quantitative estimation ...
Raja Reddy Kallem   +5 more
wiley   +1 more source

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