Results 151 to 160 of about 972,269 (340)

Standardized measurement of abdominal muscle by computed tomography: association with cardiometabolic risk in the Framingham Heart Study [PDF]

, 2022
Andreas A. Kammerlander, Asya Lyass, Taylor F. Mahoney, Jana Taron, Parastou Eslami, Michael T. Lu, Michelle T. Long, Ramachandran S. Vasan, Joseph M. Massaro, Udo Hoffmann   +9 more
openalex   +1 more source

MELODY: Mediation Analysis in Logistic Regression for High‐Dimensional Mediators and a Binary Outcome

Genetic Epidemiology, Volume 50, Issue 1, February 2026.
ABSTRACT Mediation analysis is a pivotal tool for elucidating the indirect effect of an environmental factor or treatment on disease through potentially high‐dimensional omics data, such as gene expression profiles. However, traditional mediation analysis methods tailored for binary outcomes often rely on the rare disease assumption in logistic ...
Sunyi Chi, Xingyu Li, Peng Wei, Xuelin Huang   +3 more
wiley   +1 more source

Integrative network analysis reveals molecular mechanisms of blood pressure regulation

Molecular Systems Biology, 2015
Genome‐wide association studies (GWAS) have identified numerous loci associated with blood pressure (BP). The molecular mechanisms underlying BP regulation, however, remain unclear.
Tianxiao Huan, Qingying Meng, Mohamed A Saleh, Allison E Norlander, Roby Joehanes, Jun Zhu, Brian H Chen, Bin Zhang, Andrew D Johnson, Saixia Ying, Paul Courchesne, Nalini Raghavachari, Richard Wang, Poching Liu, The International Consortium for Blood Pressure GWAS (ICBP), Christopher J O'Donnell, Ramachandran Vasan, Peter J Munson, Meena S Madhur, David G Harrison, Xia Yang, Daniel Levy   +21 more
doaj   +1 more source

Cardiovascular Challenges in Chronic Lymphocytic Leukemia (CLL) Patients Undergoing Bruton Tyrosine Kinase (BTK) Inhibitor Therapy

European Journal of Haematology, Volume 116, Issue 2, Page 104-115, February 2026.
ABSTRACT Background/Objectives Bruton tyrosine kinase inhibitors (BTKis) have revolutionized treatment for chronic lymphocytic leukemia (CLL), but cardiovascular (CV) toxicities pose significant challenges. Second‐generation BTKis offer improved target specificity, yet CV risks persist.
Stefano Oliva, Stefano Molica
wiley   +1 more source

Exploring cognitive progression subtypes in the Framingham Heart Study

Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
AbstractINTRODUCTIONAlzheimer's disease (AD) is a heterogeneous disorder characterized by complex underlying neuropathology that is not fully understood. This study aimed to identify cognitive progression subtypes and examine their correlation with clinical outcomes.METHODSParticipants of this study were recruited from the Framingham Heart Study.
Huitong Ding, Biqi Wang, Alexander P. Hamel, Cody Karjadi, Ting F. A. Ang, Rhoda Au, Honghuang Lin   +6 more
openaire   +3 more sources

II. Coronary Heart Disease in the Framingham Study [PDF]

American Journal of Public Health and the Nations Health, 1957
T R, DAWBER, F E, MOORE, G V, MANN
openaire   +4 more sources

Is the Active Involvement of Family Caregivers in Adult Hospital Care Effective to Improve Patient Outcomes? A Systematic Review

Journal of Clinical Nursing, Volume 35, Issue 2, Page 565-584, February 2026.
ABSTRACT Aim To investigate the effects of active involvement of family caregivers in adult in‐hospital care on patients' readmissions, complications, mortality, length of hospital stay, quality of life, psychological distress and activities of daily living, as well as on the satisfaction of patients, HCPs and family caregivers.
Daphne Bloemberg, Mark L. van Zuylen, Selma C. W. Musters, Demi de Jong, Anne Marthe Schreuder, Faridi S. Jamaludin, Benedikt Preckel, Els Nieveen van Dijkum, Anne M. Eskes   +8 more
wiley   +1 more source

The Gwangju Alzheimer's & Related Dementias (GARD) cohort: Over a decade of Asia's largest longitudinal multimodal study

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) is a major public health concern in Korea, with a high prevalence among older adults. A community‐based longitudinal study is essential for tracking disease progression, identifying biomarkers, and developing targeted prevention and treatment strategies.
Kyu Yeong Choi, Sarang Kang, Seungho Cook, Donghe Li, Yu Yong Choi, Eun Hyun Seo, Xudong Han, Jung Eun Park, Suyeon Lee, Sunjae Lee, Ji Yeon Chung, Ari Chong, Seong‐Min Choi, Jung‐Min Ha, Min Kyung Song, Jung Sup Lee, IL Han Choo, Ja‐Hae Kim, Ho‐Chun Song, Byeong C Kim, Hoowon Kim, Lindsay A. Farrer, Jungsoo Gim, Gyungah R. Jun, Kun Ho Lee   +24 more
wiley   +1 more source

CTE neuropathology alone is associated with dementia and cognitive symptoms

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION This studyexamined the independent contribution of chronic traumatic encephalopathy (CTE) neuropathology to symptoms. METHODS The sample included 614 brain donors with (n = 366) and without (n = 248) autopsy‐confirmed CTE. Brain donors with other major neurodegenerative disease diagnoses were excluded.
Rachael M. Layden, Jenna R. Groh, Annalise E. Miner, Abigail Kidd, Sophia B. Nosek, Stephanie Gonzalez Gil, Bobak Abdolmohammadi, Steven Lenio, Christopher J. Nowinski, Yorghos Tripodis, Brett M. Martin, Joseph N. Palmisano, Brigid C. Dwyer, Douglas I. Katz, Lee E. Goldstein, Robert C. Cantu, Robert A. Stern, Thor D. Stein, Ann C. McKee, Daniel H. Daneshvar, Jesse Mez, Michael L. Alosco   +21 more
wiley   +1 more source

General Cardiovascular Risk Profile for Use in Primary Care: The Framingham Heart Study

Circulation, 2008
R. D'Agostino, R. Vasan, M. Pencina, P. Wolf, M. Cobain, J. Massaro, W. Kannel   +6 more
semanticscholar   +1 more source