Results 41 to 50 of about 972,269 (340)

Peroxiredoxin 4, a novel circulating biomarker for oxidative stress and the risk of incident cardiovascular disease and all-cause mortality [PDF]

, 2012
BACKGROUND: Oxidative stress has been suggested to play a key role in the development of cardiovascular disease (CVD). The aim of our study was to investigate the associations of serum peroxiredoxin 4 (Prx4), a hydrogen peroxide-degrading peroxidase ...
Abbasi, A., Bakker, S.J., Beulens, J.W., Corpeleijn, E., de Jong, P.E., Gans, R.O., Gansevoort, R.T., Hillege, H.L., Navis, G., Peelen, L.M., Postmus, D., Schulte, J., Stolk, R.P., Struck, J., van der Harst, P.   +14 more
core   +2 more sources

Trends in Diabetes Incidence: The Framingham Heart Study [PDF]

Diabetes Care, 2014
OBJECTIVE Obesity and type 2 diabetes continue to increase in prevalence in the U.S. Whether diabetes incidence continues to increase in recent times is less well documented. We examined trends in diabetes incidence over the previous four decades. RESEARCH DESIGN AND
Abraham, Tobin M., Pencina, Karol M., Pencina, Michael J., Fox, Caroline S.   +3 more
openaire   +2 more sources

Circulating Galectin‐3 Is Associated With Cardiometabolic Disease in the Community

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundCirculating Galectin‐3 (Gal‐3) concentrations are associated with an increased incidence of heart failure, atrial fibrillation, chronic kidney disease, and mortality.
Matthew Nayor, Na Wang, Martin G. Larson, Ramachandran S. Vasan, Daniel Levy, Jennifer E. Ho   +5 more
doaj   +1 more source

Testing for Network and Spatial Autocorrelation

, 2020
Testing for dependence has been a well-established component of spatial statistical analyses for decades. In particular, several popular test statistics have desirable properties for testing for the presence of spatial autocorrelation in continuous ...
A Cliff, AD Cliff, CP Shapiro, CP Sison, DA Griffith, G Kossinets, G Papadogeorgou, IS Weaver, J Long, JAF Diniz-Filho, JH Fowler, JJ Lennon, JK Ord, JS Saczynski, JW Lichstein, K Fujimoto, KA O’Neil, Kevin Lewis, KP Overmars, L Anselin, NA Christakis, NA Christakis, P Legendre, PA Moran, PE Smouse, R Lyons, RB D’Agostino, RC Geary, RS Vasan, S Farber, S Farber, W Castelli, WQ Qiu   +32 more
core   +1 more source

Association of Symptoms After COVID-19 Vaccination With Anti–SARS-CoV-2 Antibody Response in the Framingham Heart Study

JAMA Network Open, 2022
This cohort study examines the association of self-reported postvaccination symptoms with anti–SARS-CoV-2 antibody response among Framingham Heart Study participants contributing to the Collaborative Cohort of Cohorts for COVID-19 Research study.
E. Hermann, Benjamin Lee, P. Balte, V. Xanthakis, B. Kirkpatrick, M. Cushman, E. Oelsner   +6 more
semanticscholar   +1 more source

Metabolomic signatures of cardiac remodelling and heart failure risk in the community

ESC Heart Failure, 2020
Aims Heart failure (HF) is associated with several metabolic changes, but it is unknown whether distinct components of the circulating metabolome may be related to cardiac structure and function, and with incident HF in the community. Methods and results
Charlotte Andersson, Chunyu Liu, Susan Cheng, Thomas J. Wang, Robert E. Gerszten, Martin G. Larson, Ramachandran S. Vasan   +6 more
doaj   +1 more source

The Collective Dynamics of Smoking in a Large Social Network [PDF]

, 2008
Based on repeated surveys of 12,067 closely interconnected people between 1971 and 2000, examines the extent to which smoking spreads socially and to which groups of smokers quit together, as well as trends in the number and social centrality of ...
James H. Fowler, Nicholas A. Christakis
core   +1 more source

Label‐Free Leukocyte Biophysical Profiling Using Impedance‐Deformability Cytometry for Rapid Cardiovascular Risk Stratification

Advanced Science, EarlyView.
This study presents an impedance‐based single‐cell profiling platform that quantifies the electrical and mechanical properties of neutrophils across in vitro, in vivo, and clinical samples. The approach reveals distinct biophysical alterations associated with type 2 diabetes (T2DM) and cardiovascular complications, suggesting its potential utility for ...
Linwei He, Hui Min Tay, Feng Chen, Hong Sheng Cheng, Liang De Wang, Qiqi Nam, Arunachalam Thannirmalai, Lingyan Gong, Aram J. Chung, Nguan Soon Tan, King Ho Holden Li, Rinkoo Dalan, Siu Ling Wong, Han Wei Hou   +13 more
wiley   +1 more source

Prevalent Cardiovascular Disease and Atrial Fibrillation in Relation to Cerebral Small Vessel Disease Burden

Brain Sciences
Background/Objectives: Cardiovascular disease (CVD) contributes to stroke and dementia. Individuals with CVD have high risk for adverse cognitive outcomes and stroke, possibly due to shared risk factors between CVD, stroke, and dementia, which may be ...
Oluchi Ekenze, Adlin Pinheiro, Alexa S. Beiser, Vasileios-Arsenios Lioutas, Hugo J. Aparicio, Emelia J. Benjamin, Ramachandran S. Vasan, Charles DeCarli, Sudha Seshadri, Serkalem Demissie, Jose R. Romero   +10 more
doaj   +1 more source

Interrelations Between Arterial Stiffness, Target Organ Damage, and Cardiovascular Disease Outcomes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Excess transmission of pressure pulsatility caused by increased arterial stiffness may incur microcirculatory damage in end organs (target organ damage [TOD]) and, in turn, elevate risk for cardiovascular disease (CVD) events.
Ramachandran S. Vasan, Meghan I. Short, Teemu J. Niiranen, Vanessa Xanthakis, Charles DeCarli, Susan Cheng, Sudha Seshadri, Gary F. Mitchell   +7 more
doaj   +1 more source