Results 41 to 50 of about 879,424 (313)

Left Ventricular Diastolic Dysfunction in the Community: Impact of Diagnostic Criteria on the Burden, Correlates, and Prognosis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundLeft ventricular diastolic dysfunction (DD) is common, particularly in women and older individuals, and it is associated with adverse cardiovascular outcomes.
Matthew Nayor, Leroy L. Cooper, Danielle M. Enserro, Vanessa Xanthakis, Martin G. Larson, Emelia J. Benjamin, Jayashri Aragam, Gary F. Mitchell, Ramachandran S. Vasan   +8 more
doaj   +1 more source

Aortic Arch Width and Cardiovascular Disease in Men and Women in the Community

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background We sought to determine whether increased aortic arch width (AAW) adds to standard Framingham risk factors and coronary artery calcium (CAC) for prediction of incident adverse cardiovascular disease (CVD) events in community‐dwelling adults ...
Michael L. Chuang, Philimon N. Gona, Saadia Qazi, Rebecca M. Musgrave, Caroline S. Fox, Joseph M. Massaro, Udo Hoffmann, Christopher J. O'Donnell   +7 more
doaj   +1 more source

ADP Platelet Hyperreactivity Predicts Cardiovascular Disease in the FHS (Framingham Heart Study)

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundPlatelet function is associated with adverse events in patients with cardiovascular disease (CVD). Methods and ResultsWe examined associations of baseline platelet function with incident CVD events in the community‐based FHS (Framingham Heart ...
Marja K. Puurunen, Shih‐Jen Hwang, Martin G. Larson, Ramachandran S. Vasan, Christopher J. O'Donnell, Geoffrey Tofler, Andrew D. Johnson   +6 more
doaj   +1 more source

Circulating Galectin‐3 Is Associated With Cardiometabolic Disease in the Community

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundCirculating Galectin‐3 (Gal‐3) concentrations are associated with an increased incidence of heart failure, atrial fibrillation, chronic kidney disease, and mortality.
Matthew Nayor, Na Wang, Martin G. Larson, Ramachandran S. Vasan, Daniel Levy, Jennifer E. Ho   +5 more
doaj   +1 more source

Metabolomic signatures of cardiac remodelling and heart failure risk in the community

ESC Heart Failure, 2020
Aims Heart failure (HF) is associated with several metabolic changes, but it is unknown whether distinct components of the circulating metabolome may be related to cardiac structure and function, and with incident HF in the community. Methods and results
Charlotte Andersson, Chunyu Liu, Susan Cheng, Thomas J. Wang, Robert E. Gerszten, Martin G. Larson, Ramachandran S. Vasan   +6 more
doaj   +1 more source

Carotid Atherosclerosis and Cerebral Microbleeds: The Framingham Heart Study [PDF]

Journal of the American Heart Association, 2016
Background Carotid atherosclerosis is associated with subclinical ischemic cerebrovascular disease, but its role in hemorrhage‐prone small vessel disease—represented by cerebral microbleed ( CMB )—is unclear, although vascular risk factors underlie both conditions. We hypothesized that
Romero, José R, Preis, Sarah R, Beiser, Alexa, DeCarli, Charles, D'Agostino, Ralph B, Wolf, Philip A, Vasan, Ramachandran S, Polak, Joseph F, Seshadri, Sudha   +8 more
openaire   +5 more sources

Mechanically Active Hydrogel for Healing Intestinal Fistulas through the YAP‐Mediated Mechanosensitization of Intestinal Epithelial Cells

Advanced Science, EarlyView.
This study develops the hydrogel with antimicrobial, adhesive, degradable, injectable, and temperature‐sensitive contraction properties based on the transcriptomic and pathological characteristics of intestinal fistula patients. This hydrogel can seal rabbit intestinal fistula in situ, reduce the intestinal defect, and promote intestinal epithelial ...
Ze Li, Jiayang Li, Kang Chen, Guiwen Qu, Shuanghong Yang, Sicheng Li, Ye Liu, Yitian Teng, Rui Ma, Jinjian Huang, Peige Wang, Jianan Ren, Xiuwen Wu   +12 more
wiley   +1 more source

Long‐Term Incidence of Dementia Following Transient Ischemic Attack: A Longitudinal Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The association between transient ischemic attack (TIA) and dementia is incompletely characterized. Determining the cognitive sequalae of TIA is important as it can function as an early warning sign or additional risk factor for dementia.
Vasileios‐Arsenios Lioutas, Gina Peloso, Jose Rafael Romero, Hugo Aparicio, Mitzi Gonzales, Amy Werry, Dibya Himali, Jayandra Himali, Ayantika Banerjee, Saptaparni Gosh, Vasan S. Ramachandran, Alexa Beiser, Sudha Seshadri   +12 more
doaj   +1 more source

Interrelations Between Arterial Stiffness, Target Organ Damage, and Cardiovascular Disease Outcomes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Excess transmission of pressure pulsatility caused by increased arterial stiffness may incur microcirculatory damage in end organs (target organ damage [TOD]) and, in turn, elevate risk for cardiovascular disease (CVD) events.
Ramachandran S. Vasan, Meghan I. Short, Teemu J. Niiranen, Vanessa Xanthakis, Charles DeCarli, Susan Cheng, Sudha Seshadri, Gary F. Mitchell   +7 more
doaj   +1 more source

High-throughput digitization of analog human echocardiography data

MethodsX, 2020
Echocardiographic imaging has been acquired in historical longitudinal cohorts of cardiovascular disease. Many cohorts were established prior to digital recording of echocardiography, and thus have preserved their archival imaging on Video Home System ...
Alan C. Kwan, Gerran Salto, Emmanuella Demosthenes, Birgitta T. Lehman, Ewa Osypiuk, Plamen Stantchev, Ramachandran S. Vasan, Susan Cheng   +7 more
doaj   +1 more source