Results 51 to 60 of about 972,269 (340)

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

Long‐Term Incidence of Dementia Following Transient Ischemic Attack: A Longitudinal Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The association between transient ischemic attack (TIA) and dementia is incompletely characterized. Determining the cognitive sequalae of TIA is important as it can function as an early warning sign or additional risk factor for dementia.
Vasileios‐Arsenios Lioutas, Gina Peloso, Jose Rafael Romero, Hugo Aparicio, Mitzi Gonzales, Amy Werry, Dibya Himali, Jayandra Himali, Ayantika Banerjee, Saptaparni Gosh, Vasan S. Ramachandran, Alexa Beiser, Sudha Seshadri   +12 more
doaj   +1 more source

Protein Biomarkers of Cardiovascular Disease and Mortality in the Community

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background The discovery of novel and highly predictive biomarkers of cardiovascular disease (CVD) has the potential to improve risk‐stratification methods and may be informative regarding biological pathways contributing to disease.
Jennifer E. Ho, Asya Lyass, Paul Courchesne, George Chen, Chunyu Liu, Xiaoyan Yin, Shih‐Jen Hwang, Joseph M. Massaro, Martin G. Larson, Daniel Levy   +9 more
doaj   +1 more source

High-throughput digitization of analog human echocardiography data

MethodsX, 2020
Echocardiographic imaging has been acquired in historical longitudinal cohorts of cardiovascular disease. Many cohorts were established prior to digital recording of echocardiography, and thus have preserved their archival imaging on Video Home System ...
Alan C. Kwan, Gerran Salto, Emmanuella Demosthenes, Birgitta T. Lehman, Ewa Osypiuk, Plamen Stantchev, Ramachandran S. Vasan, Susan Cheng   +7 more
doaj   +1 more source

Building an Intelligent Cardiovascular System Platform: Embedding Artificial Intelligence across All Facets of Cardiovascular Medicine

Advanced Intelligent Systems, EarlyView.
This paper presents an integrated AI‐driven cardiovascular platform unifying multimodal data, predictive analytics, and real‐time monitoring. It demonstrates how artificial intelligence—from deep learning to federated learning—enables early diagnosis, precision treatment, and personalized rehabilitation across the full disease lifecycle, promoting a ...
Mowei Kong, Xingwei Zhao, Qiuting Li, Yang Yu, Chunxiang Zhang   +4 more
wiley   +1 more source

Can't Patch Everything: Personalized Medicine for Cell Therapy in Dilated Cardiomyopathy

, 2021
Journal of the American Heart Association, EarlyView.
Andrew Sundin, Wayne Balkan, Joshua M. Hare   +2 more
wiley   +1 more source

Mid‐life and late‐life vascular risk factor burden and neuropathology in old age

Annals of Clinical and Translational Neurology, 2019
Objective To determine whether vascular risk factor burden in mid‐ or late‐life associates with postmortem vascular and neurodegenerative pathologies in a community‐based sample.
Sarah C. Conner, Matthew P. Pase, Herman Carneiro, Mekala R. Raman, Ann C. McKee, Victor E. Alvarez, Jamie M. Walker, Claudia L. Satizabal, Jayandra J. Himali, Thor D. Stein, Alexa Beiser, Sudha Seshadri   +11 more
doaj   +1 more source

Relations of Central Hemodynamics and Aortic Stiffness with Left Ventricular Structure and Function: The Framingham Heart Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundThe differing relations of steady and pulsatile components of central hemodynamics and aortic stiffness with cardiac dimensions and function have not been fully elucidated.
Bernhard M. Kaess, Jian Rong, Martin G. Larson, Naomi M. Hamburg, Joseph A. Vita, Susan Cheng, Jayashree Aragam, Daniel Levy, Emelia J. Benjamin, Ramachandran S. Vasan, Gary F. Mitchell   +10 more
doaj   +1 more source

The association between eicosanoids and incident atrial fibrillation in the Framingham Heart Study

Scientific Reports, 2022
Chronic inflammation is a continuous low-grade activation of the systemic immune response. Whereas downstream inflammatory markers are associated with atrial fibrillation (AF), upstream inflammatory effectors including eicosanoids are less studied.
Jelena Kornej, Maha A. Qadan, Mona Alotaibi, David R. Van Wagoner, Jeramie D. Watrous, Ludovic Trinquart, Sarah R. Preis, Darae Ko, Mohit Jain, Emelia J. Benjamin, Susan Cheng, Honghuang Lin   +11 more
doaj   +1 more source

Socio‐economic inequalities and heart failure morbidity and mortality: A systematic review and data synthesis

ESC Heart Failure, Volume 12, Issue 2, Page 927-941, April 2025.
Abstract Socio‐economic status (SES) has been associated with incident and prevalent heart failure (HF), as well as its morbidity and mortality. However, the precise nature of the relationship between SES and HF remains unclear due to inconsistent data. This study aims to provide a comprehensive assessment and data synthesis of the relationship between
Abdul Shakoor, Willemijn A. van Maarschalkerwaart, Jeroen Schaap, Rudolf A. de Boer, Nicolas M. van Mieghem, Eric H. Boersma, Loek van Heerebeek, Jasper J. Brugts, Robert M.A. van der Boon   +8 more
wiley   +1 more source