Results 61 to 70 of about 972,269 (340)

Transcriptome-wide association study of circulating IgE levels identifies novel targets for asthma and allergic diseases

open access: yesFrontiers in Immunology, 2023
Measurement of circulating immunoglobulin E (IgE) concentration is helpful for diagnosing and treating asthma and allergic diseases. Identifying gene expression signatures associated with IgE might elucidate novel pathways for IgE regulation. To this end,
Kathryn A. Recto   +19 more
doaj   +1 more source

The outcomes of electronic personal health records in patients with heart failure or coronary artery disease

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1464-1468, April 2025.
Abstract Background There are limited data on the efficacy of smartphone‐based personal health records (PHRs) in patients with cardiovascular disease. This study aimed to examine the processes, outcomes and challenges associated with the implementation of integrated PHRs in patients with heart failure (HF) or coronary artery disease (CAD). Methods This
Kotaro Nochioka   +16 more
wiley   +1 more source

Alcohol Consumption, Left Atrial Diameter, and Atrial Fibrillation

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Background Alcohol consumption has been associated with atrial fibrillation (AF) in several epidemiologic studies, but the underlying mechanisms remain unknown.
David D. McManus   +7 more
doaj   +1 more source

Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthmaResearch in context

open access: yesEBioMedicine, 2023
Summary: Background: Identifying novel epigenetic signatures associated with serum immunoglobulin E (IgE) may improve our understanding of molecular mechanisms underlying asthma and IgE-mediated diseases.
Kathryn Recto   +425 more
doaj   +1 more source

Plasma Leptin Levels and Incidence of Heart Failure, Cardiovascular Disease, and Total Mortality in Elderly Individuals [PDF]

open access: yes, 2008
OBJECTIVE: Obesity predisposes individuals to congestive heart failure (CHF) and cardiovascular disease (CVD). Leptin regulates energy homeostasis, is elevated in obesity, and influences ventricular and vascular remodeling.
Benjamin, Emelia J.   +10 more
core   +3 more sources

Epidemiology of venous thromboembolism in the Framingham Heart Study [PDF]

open access: yesThrombosis Research, 2016
Reports of the crude incidence of venous thromboembolism (VTE) in Western countries vary widely. Data regarding risk factors, incidence and recurrence of VTE from deeply-phenotyped community-based cohort studies are needed.To study the incidence, associated mortality, and predisposing factors of VTE in the prospective, longitudinal community-based ...
Marja K, Puurunen   +5 more
openaire   +2 more sources

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia   +2 more
wiley   +1 more source

Association of Circulating Adipokines With Echocardiographic Measures of Cardiac Structure and Function in a Community‐Based Cohort

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Adipokines mediate cardiometabolic risk associated with obesity but their role in the pathogenesis of obesity‐associated heart failure remains uncertain.
Beatrice von Jeinsen   +6 more
doaj   +1 more source

Application of Cardiovascular disease (CVD) risk assessment equations to the Thai population [PDF]

open access: yes, 2019
Objective: The objectives of this study are: 1.) To calculate the probability of Cardiovascular Disease (CVD) events by applying three different equations, which are: the Asia-Pacific Cohort Study (APCS) equation, the Framingham-Asia equation and the ...
Collins, Karen   +5 more
core  

Self-reported health and health care use in an ageing population in the Agincourt sub-district of rural South Africa. [PDF]

open access: yes, 2013
BACKGROUND: South Africa is experiencing a demographic and epidemiological transition with an increase in population aged 50 years and older and rising prevalence of non-communicable diseases. This, coupled with high HIV and tuberculosis prevalence, puts
Clark, Benjamin   +4 more
core   +3 more sources

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