Results 61 to 70 of about 954,894 (249)

Large-scale gene-centric analysis identifies novel variants for coronary artery disease [PDF]

, 2011
Coronary artery disease (CAD) has a significant genetic contribution that is incompletely characterized. To complement genome-wide association (GWA) studies, we conducted a large and systematic candidate gene study of CAD susceptibility, including ...
Strawbridge, Rona, The IBC 50K CAD Consortium,   +1 more
core   +1 more source

Association Between Prolactin and Incidence of Cardiovascular Risk Factors in the Framingham Heart Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundProlactin is an anterior pituitary hormone that may modulate the adverse effects of obesity. Prolactin has been associated with cardiovascular disease mortality, but less is known about whether prolactin predicts incidence of cardiovascular ...
Kate E. Therkelsen, Tobin M. Abraham, Alison Pedley, Joseph M. Massaro, Patrice Sutherland, Udo Hoffmann, Caroline S. Fox   +6 more
doaj   +1 more source

Lifetime risk of atrial fibrillation according to optimal, borderline, or elevated levels of risk factors: cohort study based on longitudinal data from the Framingham Heart Study

British medical journal, 2018
Objective To examine the association between risk factor burdens—categorized as optimal, borderline, or elevated—and the lifetime risk of atrial fibrillation. Design Community based cohort study. Setting Longitudinal data from the Framingham Heart Study.
L. Staerk, Biqi Wang, S. Preis, M. Larson, S. Lubitz, P. Ellinor, D. McManus, D. Ko, L. Weng, K. Lunetta, L. Frost, E. Benjamin, L. Trinquart   +12 more
semanticscholar   +1 more source

Author Correction: Genome‐wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease

Nature Communications, 2018
In the originally published version of this Article, financial support was not fully acknowledged. The sentence “KS was supported by the ‘Biomedical Research Program’ funds at Weill Cornell Medicine in Qatar, a program funded by the Qatar Foundation” has
Chen Yao, George Chen, Ci Song, Joshua Keefe, Michael Mendelson, Tianxiao Huan, Benjamin B. Sun, Annika Laser, Joseph C. Maranville, Hongsheng Wu, Jennifer E. Ho, Paul Courchesne, Asya Lyass, Martin G. Larson, Christian Gieger, Johannes Graumann, Andrew D. Johnson, John Danesh, Heiko Runz, Shih-Jen Hwang, Chunyu Liu, Adam S. Butterworth, Karsten Suhre, Daniel Levy   +23 more
doaj   +1 more source

Trends in excess mortality associated with atrial fibrillation over 45 years (Framingham Heart Study): community based cohort study

British medical journal, 2020
Objective To assess temporal trends in the association between newly diagnosed atrial fibrillation and death. Design Community based cohort study. Setting Framingham Heart Study cohort, in 1972-85, 1986-2000, and 2001-15 (periods 1-3, respectively), in ...
N. Vinter, Qiuxi Huang, M. Fenger-Grøn, L. Frost, E. Benjamin, L. Trinquart   +5 more
semanticscholar   +1 more source

Genome‐wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease

Nature Communications, 2018
Genetic variation can influence levels of disease-related plasma proteins and, thus, contribute to the pathogenesis of complex diseases. Here, the authors perform genome-wide QTL analysis for 71 plasma proteins to identify causal proteins for coronary ...
Chen Yao, George Chen, Ci Song, Joshua Keefe, Michael Mendelson, Tianxiao Huan, Benjamin B. Sun, Annika Laser, Joseph C. Maranville, Hongsheng Wu, Jennifer E. Ho, Paul Courchesne, Asya Lyass, Martin G. Larson, Christian Gieger, Johannes Graumann, Andrew D. Johnson, John Danesh, Heiko Runz, Shih-Jen Hwang, Chunyu Liu, Adam S. Butterworth, Karsten Suhre, Daniel Levy   +23 more
doaj   +1 more source

Adipose Tissue Depots and Their Cross‐Sectional Associations With Circulating Biomarkers of Metabolic Regulation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundVisceral adipose tissue (VAT) and fatty liver differ in their associations with cardiovascular risk compared with subcutaneous adipose tissue (SAT).
Jane J. Lee, Kathryn A. Britton, Alison Pedley, Joseph M. Massaro, Elizabeth K. Speliotes, Joanne M. Murabito, Udo Hoffmann, Cheryl Ingram, John F. Keaney, Ramachandran S. Vasan, Caroline S. Fox   +10 more
doaj   +1 more source

Long-term prognosis for individuals with hypertension undergoing coronary artery calcium scoring [PDF]

, 2015
To examine the performance of coronary artery calcification (CAC) for stratifying long-term risk of death in asymptomatic hypertensive ...
Callister, Tracy Q, Chang, Hyuk Jae, Cho, Iksung, Giambrone, Ashley E, Gransar, Heidi, Heo, Ran, Kalra, Dan K, Lin, Fay Y, Min, James K., Schulman Marcus, Joshua, Sciarretta, Sebastiano, Shaw, Leslee J, Truong, Quynh A, Valenti, Valentina, Ó. Hartaigh, Bríain   +14 more
core   +1 more source

Relationship between cardiovascular risk and lipid testing in one health care system: a retrospective cohort study. [PDF]

, 2015
BackgroundThe US Preventive Services Taskforce (USPSTF) recommends routine lipid screening beginning age 35 for men [1]. For women age 20 and older, as well as men age 20-34, screening is recommended if cardiovascular risk factors are present.
Anderson, Melissa L, Catz, Sheryl L, Fishman, Paul A, Green, Beverly B, Johnson, Ron L, McClure, Jennifer B, Reid, Robert J   +6 more
core   +1 more source

Sex-specific differences in the genetic and environmental effects on cardiac phenotypic variation assessed by echocardiography

Scientific Reports, 2023
The drivers of sexual dimorphism in heart failure phenotypes are currently poorly understood. Divergent phenotypes may result from differences in heritability and genetic versus environmental influences on the interplay of cardiac structure and function.
Honghuang Lin, Alan C. Kwan, Cecilia Castro-Diehl, Meghan I. Short, Vanessa Xanthakis, Ibrahim M. Yola, Gerran Salto, Gary F. Mitchell, Martin G. Larson, Ramachandran S. Vasan, Susan Cheng   +10 more
doaj   +1 more source