Results 71 to 80 of about 954,985 (333)

Long‐Term Incidence of Dementia Following Transient Ischemic Attack: A Longitudinal Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The association between transient ischemic attack (TIA) and dementia is incompletely characterized. Determining the cognitive sequalae of TIA is important as it can function as an early warning sign or additional risk factor for dementia.
Vasileios‐Arsenios Lioutas, Gina Peloso, Jose Rafael Romero, Hugo Aparicio, Mitzi Gonzales, Amy Werry, Dibya Himali, Jayandra Himali, Ayantika Banerjee, Saptaparni Gosh, Vasan S. Ramachandran, Alexa Beiser, Sudha Seshadri   +12 more
doaj   +1 more source

Mid‐life and late‐life vascular risk factor burden and neuropathology in old age

Annals of Clinical and Translational Neurology, 2019
Objective To determine whether vascular risk factor burden in mid‐ or late‐life associates with postmortem vascular and neurodegenerative pathologies in a community‐based sample.
Sarah C. Conner, Matthew P. Pase, Herman Carneiro, Mekala R. Raman, Ann C. McKee, Victor E. Alvarez, Jamie M. Walker, Claudia L. Satizabal, Jayandra J. Himali, Thor D. Stein, Alexa Beiser, Sudha Seshadri   +11 more
doaj   +1 more source

Interrelations Between Arterial Stiffness, Target Organ Damage, and Cardiovascular Disease Outcomes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Excess transmission of pressure pulsatility caused by increased arterial stiffness may incur microcirculatory damage in end organs (target organ damage [TOD]) and, in turn, elevate risk for cardiovascular disease (CVD) events.
Ramachandran S. Vasan, Meghan I. Short, Teemu J. Niiranen, Vanessa Xanthakis, Charles DeCarli, Susan Cheng, Sudha Seshadri, Gary F. Mitchell   +7 more
doaj   +1 more source

The association between eicosanoids and incident atrial fibrillation in the Framingham Heart Study

Scientific Reports, 2022
Chronic inflammation is a continuous low-grade activation of the systemic immune response. Whereas downstream inflammatory markers are associated with atrial fibrillation (AF), upstream inflammatory effectors including eicosanoids are less studied.
Jelena Kornej, Maha A. Qadan, Mona Alotaibi, David R. Van Wagoner, Jeramie D. Watrous, Ludovic Trinquart, Sarah R. Preis, Darae Ko, Mohit Jain, Emelia J. Benjamin, Susan Cheng, Honghuang Lin   +11 more
doaj   +1 more source

Plasma Leptin Levels and Incidence of Heart Failure, Cardiovascular Disease, and Total Mortality in Elderly Individuals [PDF]

, 2008
OBJECTIVE: Obesity predisposes individuals to congestive heart failure (CHF) and cardiovascular disease (CVD). Leptin regulates energy homeostasis, is elevated in obesity, and influences ventricular and vascular remodeling.
Benjamin, Emelia J., Fox, Caroline S., Harris, Tamara B., Kannel, William B., Levy, Daniel, Lieb, Wolfgang, Roubenoff, Ronenn, Sullivan, Lisa M., Vasan, Ramachandran S., Wang, Thomas J., Wilson, Peter W.   +10 more
core   +3 more sources

Heritability of Heart Rate Variability [PDF]

Circulation, 1999
Background —There is evolving evidence that heart rate (HR) is genetically determined. Heart rate variability (HRV) measured by power spectral analysis provides quantitative phenotypic markers of autonomic nervous system activity.
Jagmeet P. Singh, Hisako Tsuji, Christopher J. O'Donnell, Martin G. Larson, Daniel Levy, Jane C. Evans   +5 more
openaire   +3 more sources

Protective Effects of Socioeconomic Status and Lifestyle on Amyloid‐ and White Matter Hyperintensity‐Related Longitudinal Brain Atrophy and Cognitive Decline

Annals of Neurology, EarlyView.
Objective Socioeconomic status (SES) and lifestyle activities (LA) are strongly related, and both are associated with dementia risk. We investigated the influence of SES and LA on brain atrophy and cognitive decline considering amyloid‐beta (Aβ) positron emission tomography and white matter hyperintensity (WMH) load.
Dario Bachmann, Maha Wybitul, Sandro Studer, Antje Saake, Katrin Rauen, Andreas Buchmann, Bettina von Rickenbach, Esmeralda Gruber, Roger M. Nitsch, Christoph Hock, Anton Gietl, Valerie Treyer   +11 more
wiley   +1 more source

Relations of Central Hemodynamics and Aortic Stiffness with Left Ventricular Structure and Function: The Framingham Heart Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundThe differing relations of steady and pulsatile components of central hemodynamics and aortic stiffness with cardiac dimensions and function have not been fully elucidated.
Bernhard M. Kaess, Jian Rong, Martin G. Larson, Naomi M. Hamburg, Joseph A. Vita, Susan Cheng, Jayashree Aragam, Daniel Levy, Emelia J. Benjamin, Ramachandran S. Vasan, Gary F. Mitchell   +10 more
doaj   +1 more source

Transcriptome-wide association study of circulating IgE levels identifies novel targets for asthma and allergic diseases

Frontiers in Immunology, 2023
Measurement of circulating immunoglobulin E (IgE) concentration is helpful for diagnosing and treating asthma and allergic diseases. Identifying gene expression signatures associated with IgE might elucidate novel pathways for IgE regulation. To this end,
Kathryn A. Recto, Kathryn A. Recto, Tianxiao Huan, Tianxiao Huan, Dong Heon Lee, Dong Heon Lee, Gha Young Lee, Gha Young Lee, Jessica Gereige, Chen Yao, Chen Yao, Shih-Jen Hwang, Shih-Jen Hwang, Roby Joehanes, Roby Joehanes, Rachel S. Kelly, Jessica Lasky-Su, George O’Connor, Daniel Levy, Daniel Levy   +19 more
doaj   +1 more source

A Novel Cardiac Computed Tomography‐Based Calcium Scoring System for Predicting the Use of Atherectomy Devices in Severely Calcified Coronary Lesions

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Cardiac computed tomography (CT) is a well‐established process used to diagnose coronary artery disease; however, its specific advantages in predicting the use of atherectomy devices during percutaneous coronary intervention (PCI) for moderate to severe calcified lesions remain to be determined.
Yasuhiro Nakano, Masaaki Okutsu, Rissei Hino, Takuya Nagata, Kenji Sadamatsu, Takeshi Serikawa, Katsuyuki Hasegawa, Yoshihide Fujimoto, Shinichiro Yamada, Yu Takahashi, Kazumasa Kurogi, Naoki Masuda, Masataka Nakano, Sho Torii, Masaki Tanabe, Yoshihiro Takeda, Yoshihiro Noji, Tomoyasu Shin, Kohtaro Abe, Tetsuya Matoba   +19 more
wiley   +1 more source