Results 121 to 130 of about 4,621,374 (286)

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

Advanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos, Hee‐Seung Choi, Jingzhe Guo, Andrea A. Zanini, Tessa M. Burch‐Smith, Emily Snyder, Matthew Part, Wilhelmina van de Ven, Manhoi Hur, Gerd Ulrich Balcke, Alain Tissier, Quanqing Zhang, Katayoon Dehesh   +12 more
wiley   +1 more source

University Scholar Series: Kim Komenich [PDF]

, 2012
Revolution Revisited On March 21, 2012, SJSU Assistant Professor Kim Komenich spoke in the University Scholar Series hosted by Provost Ellen Junn at the Dr. Martin Luther King, Jr. Library.
Komenich, Kim
core   +1 more source

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

Potent and Selective IGF‐IIR‐Recruiting Bifunctional Molecules for Targeted Lysosomal Degradation of Extracellular and Membrane Proteins

Advanced Science, EarlyView.
Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...
Yuan Zhao, Yaxian Liao, Pengyun Li, Regina Stasser de Gonzalez, Xuankun Chen, Nicholas S. Nieto, Florence M. Brunel, Nick Cox, Joseph Stock, Matthew McHenry, Guangsen Fu, Penghsuan Huang, Wenxin Wu, Deqin Cai, Lingjun Li, Alexander N. Zaykov, Weiping Tang   +16 more
wiley   +1 more source

A Novel Condom Distribution Program for County Jail Prisoners [PDF]

, 2008
The Center for AIDS Prevention Studies (CAPS), in collaboration with the Center for Health Justice, the Forensic AIDS Project, and the San Francisco Sheriff's Department, conducted a feasibility study of a novel method of providing condoms to prisoners ...
Kate Monico Klein, Mary Sylla, Olga Grinstead Reznick   +2 more
core  

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

Advanced Science, EarlyView.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin, Supawadee Jariyasakulroj, Yang Shu, Jingyi Chen, Qing Chang, Pao‐Fen Ko, Yuyueyang Qiu, Feixiang Chen, David Ahn, Zhen Zhao, Jian‐Fu Chen   +10 more
wiley   +1 more source

Vol. 3, issue 1 [PDF]

, 2011
HELIN Conference “Solving the Puzzle” Test Drive iPads @ the Library Digital Commons: 1930 Commencement Video & More Faculty DVD: Michael Roberto Teaching Tools Sandbox Series IUG: San Francisco Will They Come?

core   +1 more source

A Murine Database of Structural Variants Identifies A Candidate Gene for a Spontaneous Murine Lymphoma Model

Advanced Science, EarlyView.
We analyzed long‐read genomic sequencing data obtained from 40 inbred mouse strains to produce a large database of structural variants. This dataset captures the major types of structural variants, which includes deletions, insertions, duplications, and inversions.
Wenlong Ren, Zhuoqing Fang, Egor Dolzhenko, Christopher T. Saunders, Zhuanfen Cheng, Victoria Popic, Gary Peltz   +6 more
wiley   +1 more source

Francisco de Holanda e o Conceito de “Pintura Animante”

Linguagens nas Artes, 2019
Francisco de Holanda and the Concept of “Ensouling Painting” Resumo: Francisco de Holanda (1517-1584), artista e teórico de arte português, revela-se como uma figura de grande envergadura na cultura do século XVI.
Thainan Noronha de Andrade
doaj  

A poorly known case of watershed transposition between the São Francisco and upper Paraná river basins

Neotropical Ichthyology
During construction of the Furnas hydroelectric power dam in the upper rio Paraná basin in the early 1960s, the rio Piumhi drainage outflow was diverted into the headwaters of the São Francisco river basin.
Orlando Moreira Filho, Paulo Andreas Buckup   +1 more
doaj   +1 more source