Results 111 to 120 of about 3,198,103 (279)
Advanced Science, EarlyView.This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva +28 more
wiley +1 more source
LIS: Localization based on an intelligent distributed fuzzy system applied to a WSN [PDF]
, 2012 The localization of the sensor nodes is a fundamental problem in wireless sensor networks. There are a lot of different kinds of solutions in the literature.
Barbancho Concejero, Julio +3 more
core
A variational approach to necklaces formation in polyelectrolytes
, 1997 By means of a variational approach we study the conditions under which a polyelectrolyte in a bad solvent will undergo a transition from a rod-like structure to a ``necklace'' structure in which the chain collapses into a series of globules joined by ...
de la Cruz, Monica Olvera +1 more
core +1 more source
Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling
Advanced Science, EarlyView.ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li +12 more
wiley +1 more source
Osteosarcoma in the Skull of a Holstein Heifer [PDF]
, 2015 A-2-years-old heifer showed a mass on the frontal part of the skull. Cytological analysis displayed pleomorphic, polyedric and fusiform cells with extracellular hyaline material.
Gimeno, Eduardo Juan +2 more
core +1 more source
Advanced Science, EarlyView.This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen +11 more
wiley +1 more source
, 2016 Postcard from Stacey Strovink, during the Linfield College Semester Abroad Program at the Universidad San Francisco de Quito in ...
Strovink, Stacey
core +1 more source
Advanced Science, EarlyView.TRPA1+αCGRP+ sensory neurons in the nodose ganglion detect external insults such as lipopolysaccharide (LPS) and interact directly with pulmonary neuroendocrine cells (PNECs), promoting their activation and proliferation. This neural‐epithelial interaction amplifies lung inflammation.
Jie Chen +16 more
wiley +1 more source
El entallador Francisco Gómez de Aguilar, un maestro inédito del Barroco extremeño [PDF]
, 1996 Datos biográficos y producción artística del maestro de arquitectura y entallador Francisco Gómez de Aguilar, vecino de Plasencia en el siglo XVIII, gracias a las aportaciones de documentación inédita.Biographical information and artistic production of ...
Martínez Díaz, José María
core +1 more source
Advanced Science, EarlyView.By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi +18 more
wiley +1 more source