Results 121 to 130 of about 849,914 (319)

Soticlestat as an adjunctive therapy in children and young adults with Dravet syndrome

open access: yesEpilepsia, EarlyView.
Overview of the phase 3 trial evaluating soticlestat as adjunctive therapy in children and young adults with Dravet syndrome. Abstract Objective This study evaluated the efficacy, safety, and tolerability of soticlestat as adjunctive therapy in children and young adults with Dravet syndrome (DS).
Joseph Sullivan   +14 more
wiley   +1 more source

Mental health impacts experienced by caregivers of people with Dravet syndrome: A systematic literature review

open access: yesEpilepsia, EarlyView.
Graphical abstract for the systematic literature review. Abstract Objective Dravet syndrome (DS) places tremendous burden on caregivers owing to the extent of required assistance and impact on daily living, as well as the risk to the individual with DS of premature mortality from sudden unexpected death in epilepsy and morbidity associated with ...
Adam Strzelczyk   +8 more
wiley   +1 more source

Women with epilepsy: Evidence‐based counseling across the lifespan

open access: yesEpilepsia, EarlyView.
Abstract Women with epilepsy (WWE) encounter distinct and evolving challenges across the lifespan that require clinical management extending beyond seizure control alone. Although awareness of sex‐specific aspects of epilepsy has increased, important gaps remain in their integration into routine care.
Barbara Tettenborn   +7 more
wiley   +1 more source

Newsletter / House of Finance, Goethe-Universität Frankfurt 1/11 [PDF]

open access: yes, 2011
Editorial: Michael Heise : The Chief Economist of Allianz SE about the economic outlook for 2011 Research Finance: Andreas Hackethal, Utpal Bhattacharya, Benjamin Loos, Simon Kaesler, Steffen Meyer : "Unbiased Financial Advice – Wanted but not Followed ...
House of Finance
core  

Oleogels as Emerging Solid Fat Substitutes: Basic Characteristics, Preparation Strategies, and Food Applications

open access: yesFood Safety and Health, EarlyView.
This article reviews the basic characteristics, factors affecting properties of oleogels, and preparation methods of oleogels. Meanwhile, their applications in meat products, dairy products, baked goods, and delivering bioactive compounds are highly summarized.
Wenyuan Zhang   +6 more
wiley   +1 more source

Moral responsibility and the principle of avoidable blame

open access: yesEthic@: an International Journal for Moral Philosophy, 2004
Many now accept that Frankfurt-style cases refute the principle of alternative possibilities (PAP). But, in this paper I argue that even if Frankfurt-style cases refute PAP they do not refute a related principle: the principle of avoidable blame (PAB ...
Gerald K. Harrison
doaj  

Frankfurt

open access: yes, 2018
This chapter details Ernst Kantorowicz's life in Frankfurt. He moved to the city on the first day of April 1931 to assume his new duties as a history professor at the university. During his first semester he offered a two-hour seminar in medieval history for beginners and gave an inaugural public lecture on “The Problem of Nobility in the Later Middle ...
openaire   +2 more sources

Detection of MSI signals from peripheral blood for monitoring response to immune checkpoint blockade therapy in patients with advanced microsatellite‐unstable gastrointestinal cancers: A pilot study

open access: yesInternational Journal of Cancer, EarlyView.
What's New? A substantial proportion of patients with microsatellite‐unstable gastrointestinal adenocarcinomas do not benefit from immunotherapy. This study demonstrates that microsatellite instability can be reliably detected in plasma‐derived extracellular vesicle DNA from patients with microsatellite‐unstable gastrointestinal cancers.
Aysel Ahadova   +16 more
wiley   +1 more source

Oxaliplatin‐induced neuropathy after total neoadjuvant therapy for rectal cancer: Dose–response relationship and impact on quality of life

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Oxaliplatin serves a key role in the treatment of rectal cancer, though it is a significant cause of chemotherapy‐induced peripheral neuropathy. As total neoadjuvant therapy, in which all therapy is given before surgery, has become more common, understanding neuropathy has grown increasingly important. This study examined neuropathy and its
Georg W. Wurschi   +29 more
wiley   +1 more source

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