Results 51 to 60 of about 14,034 (267)
Advanced Science, EarlyView.This study unveils a pathogenic axis in oral cancer where NUDT21 suppresses a tumor suppressor network, prominently PTEN, via 3'UTR lengthening. To exploit this transcriptomic vulnerability, we developed a biomimetic Nano‐APA‐editor. By delivering CRISPR/Cas9, we reprogrammed the global 3'UTR landscape, restoring multi‐target tumor suppression and ...
Yiran Ao +5 more
wiley +1 more source
Open Philosophy, 2020 Two essential Kantian insights are the significance for rationality of the capacity for criticism and the limits of cognition, discovered when criticism is pursued methodically, that are due to the perspectival character of the human standpoint.
Franks Paul
doaj +1 more source
Advanced Science, EarlyView.A high‐strength lightweight refractory high‐entropy alloy achieves extraordinary ductility owing to the introduction of coherent chemically gradient ordered nanodomains (CGONs). The CGONs not only serve as effective barriers to dislocation motion (strengthening) but also significantly promote dislocation nucleation and multiplication (ductilizing) upon
Wei Zhang +3 more
wiley +1 more source
Intrinsic Mechanical Parameters and their Characterization in Solid‐State Lithium Batteries
Advanced Energy Materials, Volume 15, Issue 11, March 18, 2025.This review focuses on the intrinsic mechanical parameters and their associated characterization in solid‐state batteries. The physical significance of mechanics parameters is introduced with exhaustive classifications by elastic, plastic deformations and fracture in bulk, adhesion, friction at interfaces, and mechanical fatigue in cells ...
Shuai Hao +5 more
wiley +1 more source
Identification of a change in climate state using regional flood data [PDF]
Hydrology and Earth System Sciences, 2002 Flood frequency analysis typically assumes that annual floods arise from a single distribution and are independent. However, there is significant evidence for the existence of persistent climate modes. Timescales associated with climate variability range
S. W. Franks, S. W. Franks
doaj
The Politics of Stalemate: Local Power, U.S. Military Bases, and the Japanese Courts
The ASIANetwork Exchange: A Journal for Asian Studies in the Liberal Arts, 2017 The continued controversy over the presence of American bases in Okinawa has once again raised the question of whether the issue will ultimately be resolved by the Japanese courts.
Luke Franks
doaj +2 more sources
Redesigning Interlayers for Anode‐Free Batteries: Harnessing Continuity and Metal Inventory
Advanced Energy Materials, EarlyView.Interlayers for anode‐free batteries must provide continuous interfacial coverage while remaining thin enough to preserve the finite cathode‐derived active‐metal inventory. This Perspective couples thin‐film closure with stoichiometric active‐metal consumption to reveal practical design windows across chemistry, substrate roughness, cathode loading ...
Rosalía Cid, Lorenzo Fallarino
wiley +1 more source
J@rgonia, 2018 I artikeln belyses hur individer upplever sjukdom och diagnos genom personliga erfarenhetsberättelser om diabetes typ 1. Med artikeln strävas efter att besvara frågorna: Hur berättar personer med diabetes typ 1 om att insjukna i diabetes?
Maria Holmberg
doaj
Crop Insurance Design and On‐Farm Risk Adaptation
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT The United States spends billions annually on crop insurance premium subsidies, yet the prevailing distance‐based guarantee design unintentionally rewards risk‐taking by linking subsidies to yield variability. We consider a simple redesign: define guarantees in terms of probability so that coverage reflects a consistent likelihood of indemnity.
Gerald Van Tassell, Alan P. Ker
wiley +1 more source
Alpha-Gal Allergy: a new threat to Appalachia
Marshall Journal of Medicine, 2021 Alpha-gal allergy, or mammalian meat allergy, is described as the development of IgE antibodies to the oligosaccharide galactose-a-1,3-galactose following a bite from the tick species Amblyomma americanum (Lone Star tick) or Dermacentor variabillis (Wood
Makala Murphy +5 more
doaj +1 more source