Status and future of recombinant adeno‐associated virus vector manufacturing
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley +1 more source
The locus coeruleus maintains core body temperature and protects against hypothermia during dexmedetomidine-induced sedation. [PDF]
Anuncibay Soto B +9 more
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ABSTRACT Nerve transfer surgery may be performed to restore sensorimotor function following peripheral nerve trauma or dysfunction. There is biological plausibility and limited correlative evidence that donor‐to‐recipient axon count ratios may impact functional outcomes.
Samuel James Ng +4 more
wiley +1 more source
Correction: Epigenome-wide association study of objectively measured physical activity in peripheral blood leukocytes. [PDF]
Fragoso-Bargas N +13 more
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Using Solid-State NMR to Understand the Structure of Plant Cellulose. [PDF]
Cresswell R +8 more
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Author Correction: Subclassification of obesity for precision prediction of cardiometabolic diseases. [PDF]
Coral DE +28 more
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Early mucosal IFN-α, IP-10, and IL-1RA and synchronized mucosal and systemic immune responses mediate COVID-19 disease progression. [PDF]
Agrawal M +15 more
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Insights from equitable governance assessments in conservation areas around the world. [PDF]
Dehmel N +28 more
europepmc +1 more source
Recent BMI acceleration identifies limits of metabolic plasticity and ectopic fat deposition
Coral D +13 more
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