Results 101 to 110 of about 9,643,615 (243)
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Addendum to A Blueprint for Ocean Energy Development 2010-2015 [PDF]
OWET convened the second annual OWET Developersʼ Summit on August 2, 2011 in Portland, Oregon. The Summit brought together participants, both new and those who had attended the first OWET Developersʼ Summit 2010, to review the Blueprint for Ocean Energy ...
Oregon Wave Energy Trust
core +4 more sources
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
The validity of the extended energy principle [PDF]
A recent analysis of plasma stability based on modifications of the extended energy principle for magnetohydrodynamic stability led to conclusions that are too optimistic. The original interpretation of this principle is indeed applicable.
Kulsrud, R. M. +2 more
core +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
The principle of fairness : theory, defence, and application [PDF]
Theories of social justice propose various principles for the just regulation of social institutions and practices. However, why should individuals comply with the rules of just social institutions?
Kim, Dong-il
core
Active inference offers a unified framework in which agents can exhibit both goal-directed and epistemic behaviors. However, implementing policy search in high-dimensional continuous action spaces presents challenges in terms of scalability and stability.
Takazumi Matsumoto +3 more
doaj +1 more source
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source
The Office of Energy Efficiency and Renewable Energy (EERE) of the U.S. Department of Energy (DOE) leads the Federal Government's efforts to provide reliable, affordable, and environmentally sound energy for America, through its 11 research, development,
Laboratory, National Renewable Energy
core +1 more source
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley +1 more source

