Results 181 to 190 of about 2,624,763 (275)

SARS-CoV-2 Omicron Variant in Human Saliva Samples in Cell-Free Form.

open access: yesJAMA Netw Open, 2023
Imai K, Ikeno R, Tanaka H, Takada N.
europepmc   +1 more source

Towards free form surfaces

open access: yes, 2001
A theoretical approach to construct free form surfaces is presented. We develop the conceps that arise when a free form surface is generated by tracing a mesh, using differentiable manifold theory, and generalizing the B-spline scheme. This approach allows to define a family of practical schemes.
Cotrina Navau, Josep   +2 more
openaire   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Highly customizable, ultrawide-temperature free-form flexible sensing electronic systems based on medium-entropy alloy paintings. [PDF]

open access: yesNat Commun
Li W   +11 more
europepmc   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Free-form catenary-inspired meta-couplers for ultra-high or broadband vertical coupling. [PDF]

open access: yesNanophotonics
Chen T   +11 more
europepmc   +1 more source

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