Results 91 to 100 of about 3,369,323 (272)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
KSCE Journal of Civil Engineering, 2015 The exterior surfaces of the free form buildings contain the panels with very complex curvature. While the panels incarnate a symbolic and remarkable building facade in the urban environment, constructing the panels is extremely complex. Because the bigger the curvatures of the panels, the more expensive the construction cost, a free-form building ...
Hyung Keun Park, Jong-Ho Ock
openaire +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Anapoles in Free-Standing III-V Nanodisks Enhancing Second-Harmonic Generation
, 2018 Nonradiating electromagnetic configurations in nanostructures open new horizons for applications due to two essential features: lack of energy losses and invisibility to the propagating electromagnetic field.
Bouravleuv, Alexei +7 more
core +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Higher Spin Gravity Amplitudes From Zero-form Charges
, 2012 We examine zero-form charges in Vasiliev's four-dimensional bosonic higher spin gravities. These are classical observables given by integrals over noncommutative twistor space of adjoint combinations of the zero-form master fields, including insertions ...
Colombo, Nicolò, Sundell, Per
core
Вестник СибАДИ, 2019 Introduction. The paper deals with the issues related to the implementation of the “quality” concept in the construction of reinforced concrete transport facilities linked with the scientific support during design and construction.
I. S. Pulyaev, S. M. Pulyaev
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
An electrochemical study of natural and chemically controlled eumelanin
APL Materials, 2017 Eumelanin is the most common form of the pigment melanin in the human body, with functions including antioxidant behavior, metal chelation, and free radical scavenging. This biopigment is of interest for biologically derived batteries and supercapacitors.
Ri Xu +5 more
doaj +1 more source