Results 81 to 90 of about 3,369,323 (272)

Symmetric Shape Transformations of Folded Shell Roofs Determining Creative and Rational Shaping of Building Free Forms

Symmetry, 2019
The paper presents an innovative approach to solving interdisciplinary problems emerging in the design process of building free forms roofed with elastically transformed corrugated shells. The effectiveness and rationality of shaping such free forms and the creativeness in searching for the parametric forms require the application of their regular and ...
Abramczyk, Jacek, Prokopska, Aleksandra
openaire   +1 more source

Preliminary mathematical and numerical transient models of convective heating and drying of a brick

MATEC Web of Conferences, 2018
The paper presents the initial approach to mathematical and numerical modelling and optimization of heat and mass transfer in elements of the masonry wall.
Łapka Piotr, Wasik Michał, Furmański Piotr, Seredyński Mirosław, Cieślikiewicz Łukasz, Pietrak Karol, Kubiś Michał, Wiśniewski Tomasz S., Jaworski Maciej   +8 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

The Tits alternative for generalized triangle groups of type (3, 4, 2) [PDF]

, 2008
A generalized triangle group is a group that can be presented in the form G = h x, y | xp = yq = w(x, y)r = 1 i where p, q, r ? 2 and w(x, y) is a cyclically reduced word of length at least 2 in the free product Zp ?
Howie, J, Williams, G
core   +1 more source

Segmented Timber Shells for Circular Construction: Relocation, Structural Assessment, and Robotic Fabrication of a Modular, Lightweight Timber Structure

Buildings
Segmented timber shells present a novel building system that utilizes modular, planar building components to create lightweight free-form structures in architecture.
Simon Bechert, Simon Aicher, Lyudmila Gorokhova, Laura Balangé, Monika Göbel, Volker Schwieger, Achim Menges, Jan Knippers   +7 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Rapid Prototyping of 3D Scaffolds for Tissue Engineering Using a Four-Axis Multiple-Dispenser Robotic System [PDF]

, 2003
A desktop rapid prototyping (RP) system has been developed to fabricate scaffolds for tissue engineering (TE) applications. The system is a computer-controlled four-axis machine with a multiple-dispenser head.
Feng, W., Fuh, J.Y.H., Geng, L., Hutmacher, D.W., Loh, H.T., Wong, Y.S.   +5 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Towards Sustainable Design: A Shape Optimization Framework for Climate-Adaptive Free-Form Roofs in Hot Regions

Applied Sciences
This study proposes a cross-disciplinary computational framework to advance the sustainable design of free-form grid roofs in hot climates, integrating architectural geometry with building thermal performance to enhance climate adaptability.
Bowen Hou, Baoshi Jiang, Bangjian Wang
doaj   +1 more source