Results 221 to 230 of about 78,170 (303)

New insights into epileptic spasm generation and treatment from the TTX animal model

open access: yesEpilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann   +2 more
wiley   +1 more source

Calcitonin gene‐related peptide concentration in cerebrospinal fluid and serum in horses affected by trigeminal‐mediated headshaking

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Trigeminal‐mediated headshaking (TMHS) in horses shares clinical features with human trigeminal neuralgia (HTN). Increased levels of the neuropeptide calcitonin gene‐related peptide (CGRP) have been found in the blood and cerebrospinal fluid (CSF) of HTN patients. Inhibition of CGRP in humans has shown promise for pain relief.
Lisa Annabel Weber   +7 more
wiley   +1 more source

Development of the Human–Equine Attachment Scale

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Human–horse relationships encompass diverse roles, from companion to competition partner. The impact of such bonds informs owner decision‐making regarding horse management and veterinary care, yet standardised instruments to measure these unique bonds are limited.
Richard H. Corrigan   +5 more
wiley   +1 more source

Validation of a handheld smartphone markerless gait‐analysis tool using an estimated groundline in horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background A handheld smartphone‐based computer vision algorithm (RealHorse® [RH]) offers accessible alternatives for equine gait analysis but requires validation against a gold‐standard three‐dimensional multicamera optical motion capture system (Qualisys® [QS]).
Karsten Key   +4 more
wiley   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy