Results 121 to 130 of about 1,034 (173)

Multifunctional Gold Nanocluster‐Based PROTAC System for Targeted Degradation of Phosphorylated Tau and Modulation of Neuroinflammation in Alzheimer's Disease

Advanced Functional Materials, EarlyView.
We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins, Callan D. McLoughlin, Wan‐Kyu Ko, Hye Kyu Choi, Brandon Conklin, Joshua B. Stein, Yannan Hou, Hongwon Kim, Rohan Khulbe, Ki‐Bum Lee   +9 more
wiley   +1 more source

Commodity risk assessment of debarked conifer wood chips fumigated with sulfuryl fluoride from the US. [PDF]

EFSA J
EFSA Panel on Plant Health (PLH), Vicent Civera A, Baptista P, Berlin A, Chatzivassiliou E, Cubero J, Cunniffe N, de la Peña E, Desneux N, Di Serio F, Filipiak A, Hasiow-Jaroszewska B, Jactel H, Landa B, Maistrello L, Makowski D, Milonas P, Papadopoulos NT, Potting R, Susi H, Van Der Gaag DJ, Battisti A, Bragard C, Magnusson C, Mas H, Rigling D, Faccoli M, Mikulová A, Stergulc F, Christoph E, Mosbach-Schulz O, Streissl F, Gonthier P.   +32 more
europepmc   +1 more source

Bioinspired Mechanically Robust Organic–Inorganic Hybridized Bio‐Adhesives With up to 50% Inorganic Components by Bi‐Continuous Phase Engineering

Advanced Functional Materials, EarlyView.
A robust plant protein adhesive was prepared by fabricating a bi‐continuous organic–inorganic hybrid structure. Compared with traditional organic–inorganic hybrid adhesives, the addition amount of inorganic phase is increased from 0.2%–3.0% to 50%, and the strength and toughness are increased by 6 and 121 times, respectively.
Zheng Liu, Wenlong Luo, Xu Yang, Xin Zhang, Yuru Zhu, Jingchao Li, Jianzhang Li, Jing Luo, Zhezhe Zhou, Pingan Song, Qiang Gao   +10 more
wiley   +1 more source

Effects of vatinoxan on gastrointestinal motility, sedation, and antinociception during and after long-lasting detomidine infusion in horses. [PDF]

Equine Vet J
Obrochta B, Tapio H, Raekallio M, Gracia Calvo LA, Pöyhönen RR, Hagman K, Jantunen N, Karikoski N.   +7 more
europepmc   +1 more source

Reduced Graphene Oxide Transparent Electrodes Enabling Compact Soft Tunable Lenses

Advanced Functional Materials, EarlyView.
By spray‐coating an elastomeric membrane with reduced graphene oxide (rGO) at various surface densities, elastomeric actuators are manufactured. Electro‐mechano‐optical characterizations show the suitability of rGO as an effective material for compliant, semi‐transparent electrodes, enabling soft electrically tunable lenses with a compact form factor ...
Giacomo Sasso, Alec Lamoreux, Nicola Pugno, James J. C. Busfield, Federico Carpi   +4 more
wiley   +1 more source

Hydrodynamic performances of vertical wall type breakwater with slotted barriers: a physical and numerical approach. [PDF]

Sci Rep
Kumaran V, Venkateswarlu V, Manu.
europepmc   +1 more source

Thermally Pre‐Formed Reconfigurable Resistive Random‐Access Memory Crossbar Arrays: A Dual‐Mode Platform for Robust Physically Unclonable Functions and In‐Memory Computing

Advanced Functional Materials, EarlyView.
A reconfigurable RRAM platform utilizing thermally pre‐formed filaments (TPFs) is developed to realize robust hardware security. By exploiting the thermodynamic stochasticity of TPFs, exceptionally reliable physically unclonable functions (PUFs) are achieved.
Seongbin Kwon, Taewon Lee, Dohyeong Kim, Sungmin Hwang, Sungjoon Kim   +4 more
wiley   +1 more source

Effects of Salt Stress on Earthworm Function and Compost Quality During Vermicomposting of Kitchen Wastes. [PDF]

Bioengineering (Basel)
Mao H, Ding J, Huang W, Huang K, Yang R.
europepmc   +1 more source

Atomized Oxidative Polymerization as a 3D Printing Platform for Binder‐Free, Bulk Conductive Polymer Architectures

Advanced Functional Materials, EarlyView.
Co‐delivery of electrosprayed EDOT and oxidant enables bulk oxidative polymerization during layer‐by‐layer fabrication, creating stable, highly conductive 3D PEDOT structures. This Atomized Oxidative Polymerization (AOP) overcomes the surface deposition‐only and matrix‐limited conductivity of conventional Vapor Phase Polymerization (VPP) and PEDOT:PSS ...
Tazdik Patwary Plateau, Hiep Pham, Jonghyun Park   +2 more
wiley   +1 more source