Results 241 to 250 of about 22,464,032 (340)

Animal rabies prevention and control in Shanghai, China: policies and practices, 2011-2025. [PDF]

Front Public Health
Zhu T, Chang X, Wu X, Xia L, Zhu X, Zhu J, Li Z, Chen W, Fan Y, Tang Y, Liu J, Zhao H.   +11 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Abnormal carnitine concentrations in critical illness associated with compromised outcome. [PDF]

Crit Care
Lauwers C, Langouche L, Güiza Grandas F, Pardo E, Mebis L, Vander Perre S, Wouters P, Vermeersch P, Van den Berghe G, Gunst J, Casaer MP.   +10 more
europepmc   +1 more source

Free association

Comprehensive Psychiatry, 1960
openaire   +2 more sources

Chronic thyrotoxic myopathy in an 81-year-old man with Graves disease. [PDF]

CMAJ
Nishizawa T, Ueda T.
europepmc   +1 more source

Prognostic value of FDG-PET SUV changes in cervical cancer following radiation therapy: a retrospective cohort study. [PDF]

Arch Gynecol Obstet
Bale CA, Pearce JV, Deng X, Bandyopadhyay D, Yarden N, Sport C, Miller DT, Randall LM, Fields E, Sullivan SA.   +9 more
europepmc   +1 more source

Charalampos I. Chrysafis / Andreas Hartmann / Christopher Schliephake u. a. (Hrsg.), Basileus eirenophylax. Friedenskultur(en) und monarchische Repräsentation in der Antike. Stuttgart, Steiner 2023

Historische Zeitschrift
Free Alexander
doaj   +1 more source