Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity
This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao +11 more
wiley +1 more source
Overexpression of c-Myc triggers p62 aggregation-mediated mitochondrial mitophagy in cabozantinib resistance of hepatocellular carcinoma. [PDF]
Yang K +11 more
europepmc +1 more source
Sample preparation and data collection for serial block face scanning electron microscopy of mammalian cell monolayers. [PDF]
Antao NV +5 more
europepmc +1 more source
Robust Skin-Conformal Nano-Electrodes for Sustainable Health and Performance Monitoring. [PDF]
Kim J +7 more
europepmc +1 more source
The Marine Natural Compound Aplysinamisine I Selectively Induces Apoptosis and Exhibits Synergy with Taxol™ in Triple-Negative Breast Cancer Spheroids. [PDF]
Guzmán EA +3 more
europepmc +1 more source
Exploring Cannabidiol (CBD) and Cannabigerol (CBG) Safety Profile and Skincare Potential. [PDF]
Luz-Veiga M +8 more
europepmc +1 more source
Cosmeceuticals: A transit state from synthetic to natural.
Sathyaseelan S, Rao BH, Anushmati S.
europepmc +1 more source
Free and Adherent Beauty: A Modest Proposal
The British Journal of Aesthetics, 2002Examinant la distinction entre beaute libre et beaute par adhesion dans la «Critique du jugement», l'A. analyse les trois approches differentes du concept de beaute par adhesion chez Kant, et montre qu'elle representent trois interpretations de la relation entre la forme, la fonction et les contraintes et le plaisir dans l'experience esthetique.
openaire +1 more source
Beautiful Surfaces: Kant on Free and Adherent Beauty in Nature and Art
British Journal for the History of Philosophy, 2008In contrast to rationalist views about beauty as a sort of perfection, Kant argues that judgements of taste about beauty are ‘entirely independent from the concept of perfection’ (5: 226).1 In the ...
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