Results 91 to 100 of about 1,196,996 (342)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Why are probabilistic laws governing quantum mechanics and neurobiology?

, 2004
We address the question: Why are dynamical laws governing in quantum mechanics and in neuroscience of probabilistic nature instead of being deterministic?
Abbot, Albert, Albert, Amit, Amit, Amit, Amit, Amit, Avelino, Bak, Bak, Barabasi, Barabasi, Battye, Benzi, Bliss, Bohland, Byrne, Coffins, Courant, Douglass, El Naschie, El Naschie, Ferster, Feynman, Grammaitoni, Grumbacher, Hebb, Helmut Kröger, Hertz, Hertz, Hopfield, Itzykson, James, Jeong, Kandel, Kleinberg, Kröger, Kröger, Lago-Fernandez, Laskar, Levin, Linsker, Longtin, Messiah, Metropolis, Moss, Murray, Nicholis, Noest, Nozaki, O’Dell, Peebles, Penrose, Rattay, Schuman, Squire, Strogatz, Sussman, Thompson, Tolhurst, von der Malsburg, von der Malsburg, Watts, Watts, Watts, Webb, Wiesenfeld, Wilson   +68 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Donation without Domination: Private Charity and Republican Liberty [PDF]

, 2018
Contemporary republicans have adopted a less-than-charitable attitude toward private beneficence, especially when it is directed to the poor, worrying that rich patrons may be in a position to exercise arbitrary power over their impoverished clients ...
Abizadeh, Andreoni, Andreoni, Andreoni, Bailey, Buder, Cloward, Dempsey, DeNavas-Walt, Foucault, Hall, Halpin, Hawley, Hochman, List, Lovett, Lovett, Mill, Mudge, Nicholson, OECD, Parijs, Parijs, Payne, Pettit, Pettit, Pettit, Pettit, Pettit, Rawls, Searing, Simmons, Sparling, Stigler, Stilz, Sullivan, Taylor, Tobin, Viscusi, Zakaras   +39 more
core   +1 more source

Taking the Operant Paradigm into the Field: Associative Learning in Wild Great Tits

PLoS ONE, 2015
Associative learning is essential for resource acquisition, predator avoidance and reproduction in a wide diversity of species, and is therefore a key target for evolutionary and comparative cognition research.
J. Morand‐Ferron, Steven Hamblin, E. Cole, L. Aplin, J. Quinn   +4 more
semanticscholar   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Psycholinguistic Analysis of the Structure of the Association Area of the Stimulus Competence

Психолінгвістика, 2018
The article deals with the analysis of the association area structure of the notion of competence based on the results of the free association experiment.
Tamara Sharavara, Anatolii Kotsur, Nataliia Syzonenko, Yanina Tahiltseva   +3 more
doaj   +1 more source

Poly(thioether) vitrimers via transalkylation of trialkylsulfonium salts [PDF]

, 2017
Vitrimers are permanently cross-linked organic polymers that can be reshaped, molded, and recycled without loss of network integrity. Herein, we report poly(thioether) networks, prepared through a straightforward thiol-ene photopolymerization, that can ...
Hendriks, Benjamin, Waelkens, Jelle, Winne, Johan, Du Prez, Filip   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source