Results 101 to 110 of about 1,196,996 (342)

Role of the mesoamygdaloid dopamine projection in emotional learning [PDF]

open access: yes, 2010
Amygdala dopamine is crucially involved in the acquisition of Pavlovian associations, as measured via conditioned approach to the location of the unconditioned stimulus (US).
AA Grace   +60 more
core   +1 more source

Safety signals as instrumental reinforcers during free-operant avoidance

open access: yesLearning & memory (Cold Spring Harbor, N.Y.), 2014
Safety signals provide “relief” through predicting the absence of an aversive event. At issue is whether these signals also act as instrumental reinforcers. Four experiments were conducted using a free-operant lever-press avoidance paradigm in which each
A. Fernando   +4 more
semanticscholar   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Evidence for preferential attachment: Words that are more well connected in semantic networks are better at acquiring new links in paired-associate learning

open access: yesPsychonomic Bulletin & Review, 2020
Here, we view the mental lexicon as a semantic network where words are connected if they are semantically related. Steyvers and Tenenbaum ( Cognitive Science, 29 , 41–78, 2005 ) proposed that the growth of semantic networks follows preferential ...
Matthew H. C. Mak, Hope Twitchell
semanticscholar   +1 more source

The Image of Ukraine Through Regions: The Actual Experience with Free Association Method [PDF]

open access: yesAdvances in Social Science, Education and Humanities Research, 2021
Olga Bezrukova, Alla Petrenko-Lysak
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

COMPARATIVE ANALYSIS OF FRAGMENTS OF RUSSIAN AND ITALIAN LANGUAGE CONSCIOUSNESS

open access: yesPolylinguality and Transcultural Practices, 2016
The article presents the first results of the free associative experiment and examines the problem of interlingual equivalence between some stimulus words.
T S Elizarova
doaj  

Predicting and Explaining Human Semantic Search in a Cognitive Model

open access: yes, 2017
Recent work has attempted to characterize the structure of semantic memory and the search algorithms which, together, best approximate human patterns of search revealed in a semantic fluency task.
Miscevic, Filip   +2 more
core   +1 more source

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