Results 131 to 140 of about 1,196,996 (342)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

STRUCTURE AND CONTENT OF THE IMAGE EMPIREIN LINGUISTIC CONSCIOUSNESS OF THE MODERN ADOLESCENT (13-15 YEARS): EXPERIMENTAL RESEARCH

open access: yesPolylinguality and Transcultural Practices, 2015
The article is dedicated to the problem of the influence of the computer games the linguistic consciousness of the modern adolescent. The subject of the research is the changing of the meaning of a word understood as a “subjective content of the sign ...
Nina V Schennikova
doaj  

Psycholinguistic Peculierities of the Assimilation of Angloamericanisms by the Speakers of Ukrainian-English Bilingualism

open access: yesПсихолінгвістика, 2018
The article deals with the problem of psycholinguistic peculiarities of the use of the American-English loans. The main task of the research is to educe the features of their assimilation by the students in the conditions of educational bilingualism. The
Tetyana Leleka, Olena Moskalenko
doaj   +1 more source

Fear in horses [PDF]

open access: yes, 2006
Fear is generally considered to be an undesirable emotional state that may reduce welfare, growth and reproductive performance in animals. Fear in horses is additionally problematic, because fear reactions can cause serious injury to both horse and human.
Christensen, Janne Winther
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

ETHNIC STEREOTYPES OF THE VOLGA TATARS IN ORDINARY LANGUAGE CONSCIOUSNESS OF RUSSIANS AND THE TATARS OF THE REPUBLIC OF TATARSTAN

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics, 2017
In the article, based on the interpretation of the experimental material, the content of the ethnic image of the Volga Tatars is determined. The relevance of the study is explained by the fact that the description of the content of the images: “yourself”
Anna V Razumkova
doaj   +1 more source

Associative learning in baboons and humans: Species differences in learned attention to visual features [PDF]

open access: yes, 1998
We examined attention shifting in baboons and humans during the learning of visual categories. Within a conditional matching-to-sample task, participants of the two species sequentially learned two two-feature categories which shared a common feature ...
Fagot, J, Kruschke, J K, Vauclair, J
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Signaling in The Prefrontal Cortex Modulates Cued Fear Learning, But Not Spatial Working Memory, in Female Rats [PDF]

open access: yes, 2018
A genetic polymorphism within the gene encoding the pituitary adenylate cyclase- activating polypeptide (PACAP) receptor type I (PAC1R) has recently been associated with hyper-reactivity to threat-related cues in women, but not men, with post-traumatic ...
Gilmartin, Marieke R.   +6 more
core   +1 more source

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