Results 141 to 150 of about 1,196,996 (342)

The quantum-to-classical transition: contraction of associative products

open access: yes, 2016
The quantum-to-classical transition is considered from the point of view of contractions of associative algebras. Various methods and ideas to deal with contractions of associative algebras are discussed that account for a large family of examples. As an
Ibort, A.   +5 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

IMAGE OF FAMILY IN THE LINGUISTIC CONSCIOUSNESS OF NATIVE SPEAKERS IN DIFFERENT LINGUACULTURES (ON THE EXAMPLE OF RUSSIA AND SRI LANKA)

open access: yesФилологический класс, 2019
The aim of this research is to identify and describe the similarities and differences in the image of the family among native speakers of Russian and Sri Lankan linguacultures.
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Hand to mouth: automatic imitation across effector systems [PDF]

open access: yes, 2007
The effector-specificity of automatic imitation was investigated using a stimulus-response compatibility (SRC) procedure in which participants were required to make an open or a close response with either their hand or their mouth.
Heyes, C., Leighton, J.
core  

Free-energy profiles along reduction pathways of MoS2 M-edge and S-edge by dihydrogen: a first-principles study

open access: yes, 2011
We present the results of DFT calculations of free energy profiles along the reaction pathways starting from 50% coverage of MoS2 M-edge and 100% coverage of S-edge by sulfur, and leading to 37% coverage, i.e.
Prodhomme, Pierre-Yves   +2 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Transient Dynamics of Sparsely Connected Hopfield Neural Networks with Arbitrary Degree Distributions

open access: yes, 2007
Using probabilistic approach, the transient dynamics of sparsely connected Hopfield neural networks is studied for arbitrary degree distributions. A recursive scheme is developed to determine the time evolution of overlap parameters.
Amari   +29 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

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