FEBS Open Bio, EarlyView.CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
The conditions of failing and successful plant invasions with free boundary. [PDF]
Sci RepLi R, Zhu L, Zhou Y.
europepmc +1 more source
Elastodynamics of a quarterspace with one boundary semi-rigid and the other stress-free [PDF]
, 1988 Pratap N. Sahay, A. Z. Capri
openalex +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
C ∞ regularity in semilinear free boundary problems. [PDF]
Math AnnRestrepo D, Ros-Oton X.
europepmc +1 more source
Closure to “Discussion of ‘First-Order Perturbations of Laminar Free-Convection Boundary Layers on a Vertical Plate’” (1964, ASME J. Heat Transfer, 86, p. 114) [PDF]
, 1964 Kwang-Tzu Yang, Edward W. Jerger
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Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Static and Free-Boundary Vibration Analysis of Egg-Crate Honeycomb Core Sandwich Panels Using the VAM-Based Equivalent Model. [PDF]
Materials (Basel)Li R +5 more
europepmc +1 more source
The pattern of allied post-war diplomacy : the problems of the Italo-Yugoslav boundary disputes and the free territory of Trieste, July 17, 1945-March 20, 1948 [PDF]
, 1961 George V. Kacewicz +1 more
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Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source